Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 2/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.39 |
| ▸ | CDC25C | P30307 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15488872 | 0.94 | MAPT (0.45) | MAPTL3MBTL1TSHRCYP1A2CYP3A4 | |
| SCHEMBL11274067 | 0.86 | MAPT (0.51) | MAPTL3MBTL1TSHRCYP1A2CYP3A4 | |
| SCHEMBL13296552 | 0.85 | ALDH1A1 (0.47) | MAPTL3MBTL1TSHRCYP3A4MAPK1 | |
| SCHEMBL11274071 | 0.83 | MAPT (0.51) | MAPTL3MBTL1TSHRCYP1A2CYP3A4 | |
| SCHEMBL5667391 | 0.82 | MAPT (0.48) | MAPTL3MBTL1TSHRCYP1A2CYP3A4 | |
| SCHEMBL5010052 | 0.82 | MAPT (0.68) | MAPTL3MBTL1TSHRCYP1A2CYP3A4 | |
| SCHEMBL17124187 | 0.82 | MAPT (0.68) | MAPTL3MBTL1TSHRCYP1A2CYP3A4 | |
| SCHEMBL15488871 | 0.79 | ALDH1A1 (0.45) | MAPTL3MBTL1TSHRCYP3A4TDP1 | |
| SCHEMBL11583222 | 0.78 | ALDH1A1 (0.50) | MAPTL3MBTL1TSHRCYP3A4MAPK1 | |
| SCHEMBL160430 | 0.75 | ALDH1A1 (0.57) | MAPTL3MBTL1TSHRCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10399955-B2 | 3,6-disubstituted xanthylium salts | WISTA LABORATORIES LTD. (SG) | 2019-09-03 | — | — | US | disclosed |
| US-20170088534-A1 | 3,6-DISUBSTITUTED XANTHYLIUM SALTS | WISTA LABORATORIES LTD. (SG) | 2017-03-30 | — | — | US | disclosed |
| US-9549933-B2 | 3,6-disubstituted xanthylium salts | WISTA LABORATORIES LTD. (SG) | 2017-01-24 | — | — | US | disclosed |
| EP-2373660-B1 | 3,6-DISUBSTITUTED XANTHYLIUM SALTS AS MEDICAMENTS | WISTA LAB LTD (SG) | 2016-08-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10399955-B2 | 3,6-disubstituted xanthylium salts | MAPT, PSEN2, PSEN1 | MAPT 1/4885L3MBTL1 2899/4885TSHR 4188/4885 |
| US-20170088534-A1 | 3,6-DISUBSTITUTED XANTHYLIUM SALTS | MAPT, PSEN2, PSEN1 | MAPT 1/4885L3MBTL1 2899/4885TSHR 4188/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.