Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | TSHR | P16473 | 4/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.51 |
| ▸ | S100B | P04271 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | GRK6 | P43250 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 2/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11274067 | 0.90 | MAPT (0.51) | MAPTTSHRL3MBTL1TDP1CYP3A4 | |
| SCHEMBL5007900 | 0.84 | GRK6 (0.48) | MAPTTSHRL3MBTL1TDP1CYP3A4 | |
| SCHEMBL18022811 | 0.83 | MAPT (0.50) | MAPTTSHRL3MBTL1TDP1CYP3A4 | |
| SCHEMBL5010052 | 0.83 | MAPT (0.68) | MAPTTSHRL3MBTL1TDP1CYP3A4 | |
| SCHEMBL29479937 | 0.81 | ALDH1A1 (0.56) | MAPTTSHRL3MBTL1TDP1CYP3A4 | |
| SCHEMBL11520124 | 0.81 | GRK6 (0.48) | MAPTTSHRL3MBTL1TDP1CYP3A4 | |
| SCHEMBL5667391 | 0.81 | MAPT (0.48) | MAPTTSHRL3MBTL1TDP1CYP3A4 | |
| SCHEMBL15488872 | 0.81 | MAPT (0.45) | MAPTTSHRL3MBTL1TDP1CYP3A4 | |
| SCHEMBL5555831 | 0.80 | S100B (0.44) | MAPTTSHRL3MBTL1CYP3A4CYP1A2 | |
| SCHEMBL5554872 | 0.79 | ALDH1A1 (0.44) | MAPTTSHRTDP1CYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4332884-A | USING A DIOXIME CHELATING AGENT | RICOH CO., LTD. (JP) | 1982-06-01 | — | — | US | disclosed |
| US-4306014-A | AMMONIA OR AMINES SUPPRESS THE COLOR-FORMING REACTION SYSTEM | RICOH CO., LTD. (JP) | 1981-12-15 | — | — | US | disclosed |