Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.68 |
| ▸ | TSHR | P16473 | 1/20 | 0.68 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.68 |
| ▸ | CDC25C | P30307 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | BAZ1A | Q9NRL2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30327116 | 0.88 | MAPT (0.59) | MAPTL3MBTL1MAPK1CYP1A2CYP3A4 | |
| SCHEMBL6558976 | 0.82 | MAPT (1.00) | MAPTL3MBTL1MAPK1CYP1A2CYP3A4 | |
| SCHEMBL18022811 | 0.82 | MAPT (0.50) | MAPTL3MBTL1MAPK1CYP1A2CYP3A4 | |
| SCHEMBL11672106 | 0.80 | ALDH1A1 (0.43) | MAPTL3MBTL1MAPK1CYP1A2CYP3A4 | |
| SCHEMBL6556764 | 0.78 | MAPT (0.68) | MAPTL3MBTL1MAPK1CYP1A2CYP3A4 | |
| SCHEMBL30054040 | 0.78 | MAPT (0.68) | MAPTL3MBTL1MAPK1CYP1A2CYP3A4 | |
| SCHEMBL15488872 | 0.77 | MAPT (0.45) | MAPTL3MBTL1MAPK1CYP1A2CYP3A4 | |
| SCHEMBL218018 | 0.75 | MAPT (0.78) | MAPTL3MBTL1MAPK1CYP1A2CYP3A4 | |
| SCHEMBL6556773 | 0.75 | MAPT (0.62) | MAPTL3MBTL1MAPK1CYP1A2CYP3A4 | |
| SCHEMBL11583222 | 0.74 | ALDH1A1 (0.50) | MAPTL3MBTL1MAPK1CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150276751-A1 | REAGENT FOR IMAGING INTRACELLULAR ACETYLATION | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2015-10-01 | — | — | US | disclosed |
| US-20150276751-A1 | REAGENT FOR IMAGING INTRACELLULAR ACETYLATION | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2015-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150276751-A1 | REAGENT FOR IMAGING INTRACELLULAR ACETYLATION | ACAT1, ACAT2, ACAA2 | MAPT 1007/4885L3MBTL1 2819/4885MAPK1 4285/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.