Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 2/20 | 0.31 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.30 |
| ▸ | PTPRC | P08575 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PLK4 | O00444 | 1/20 | 0.30 |
| ▸ | AURKA | O14965 | 1/20 | 0.30 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5918737 | 0.91 | ALDH1A1 (0.54) | MAPK1ALDH1A1NPC1NFKB1RAB9A | |
| SCHEMBL66251 | 0.91 | ALDH1A1 (0.54) | MAPK1ALDH1A1NPC1NFKB1RAB9A | |
| SCHEMBL25580064 | 0.88 | PTGS2 (0.33) | MAPK1ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL25580048 | 0.88 | PTGS2 (0.33) | MAPK1ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL25580039 | 0.88 | PTGS2 (0.33) | MAPK1ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL15662815 | 0.88 | ALDH1A1 (0.54) | MAPK1ALDH1A1NPC1NFKB1RAB9A | |
| SCHEMBL16577756 | 0.88 | ALDH1A1 (0.54) | MAPK1ALDH1A1NPC1NFKB1RAB9A | |
| SCHEMBL15662355 | 0.88 | ALDH1A1 (0.54) | MAPK1ALDH1A1NPC1NFKB1RAB9A | |
| SCHEMBL4608172 | 0.88 | ALDH1A1 (0.54) | MAPK1ALDH1A1NPC1NFKB1RAB9A | |
| SCHEMBL5918721 | 0.87 | ALDH1A1 (0.46) | MAPK1ALDH1A1NPC1NFKB1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160240784-A1 | INDENOTRIPHENYLENE-BASED AMINE DERIVATIVE FOR ORGANIC ELECTROLUMINESCENT DEVICE | NINGBO LUMILAN ADVANCED MATERIALS CO., LTD. (CN) | 2016-08-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160240784-A1 | INDENOTRIPHENYLENE-BASED AMINE DERIVATIVE FOR ORGANIC ELECTROLUMINESCENT DEVICE | AHR, MLLT1, AR | MAPK1 3919/4885ALDH1A1 861/4885NPC1 2580/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.