Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | PAM | P19021 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2770965 | 0.81 | KDM4E (0.55) | KDM4EMAOBIDO1PAMHTR2A | |
| SCHEMBL2770961 | 0.81 | KDM4E (0.55) | KDM4EMAOBIDO1PAMHTR2A | |
| SCHEMBL4073166 | 0.79 | MAOB (0.58) | KDM4EMAOBIDO1PAMHTR2A | |
| SCHEMBL18025762 | 0.79 | MAOB (0.58) | KDM4EMAOBIDO1PAMHTR2A | |
| SCHEMBL2189821 | 0.77 | KDM4E (0.52) | KDM4EMAOBIDO1PAMHTR2A | |
| SCHEMBL17066108 | 0.77 | KDM4E (0.52) | KDM4EMAOBIDO1PAMHTR2A | |
| SCHEMBL6114073 | 0.77 | KDM4E (0.52) | KDM4EMAOBIDO1PAMHTR2A | |
| SCHEMBL11445050 | 0.77 | IDO1 (0.52) | KDM4EMAOBIDO1PAMHTR2A | |
| SCHEMBL11597360 | 0.77 | PRMT1 (0.55) | KDM4EMAOBIDO1PAMHTR2A | |
| SCHEMBL14275030 | 0.77 | KDM4E (0.52) | KDM4EMAOBIDO1PAMHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006047167-A2 | 9 ALKYL AND 9 ALKYLIDENYL 6-0 ALKYL-11, 12 CARBAMATE KETOLIDE ANTIMICROBIALS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2006-05-04 | — | — | WO | disclosed |