SCHEMBL2770965

SCHEMBL2770965

C(=Cc1ccccc1)CNCC=Cc1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.55
RAB9A P51151 1/20 0.54
ALDH1A1 P00352 2/20 0.51
IDO1 P14902 2/20 0.50
MAOB P27338 2/20 0.50
PAM P19021 1/20 0.50
PRMT1 Q99873 1/20 0.50
HTR2A P28223 3/20 0.47
TRPA1 O75762 1/20 0.46
LMNA P02545 1/20 0.46
ALOX5 P09917 1/20 0.46
MAPK1 P28482 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2770961 1.00 KDM4E (0.55) KDM4ERAB9AALDH1A1IDO1MAOB
SCHEMBL14275030 0.91 KDM4E (0.52) KDM4ERAB9AALDH1A1IDO1MAOB
SCHEMBL11597360 0.91 PRMT1 (0.55) KDM4ERAB9AALDH1A1IDO1MAOB
SCHEMBL11597357 0.91 PRMT1 (0.55) KDM4ERAB9AALDH1A1IDO1MAOB
SCHEMBL3884865 0.89 RAB9A (0.47) KDM4ERAB9AALDH1A1IDO1MAOB
SCHEMBL3884868 0.89 RAB9A (0.47) KDM4ERAB9AALDH1A1IDO1MAOB
SCHEMBL2189374 0.87 RAB9A (0.53) KDM4ERAB9AALDH1A1IDO1MAOB
SCHEMBL4356479 0.87 RAB9A (0.49) KDM4ERAB9AALDH1A1IDO1MAOB
SCHEMBL4356484 0.87 RAB9A (0.49) KDM4ERAB9AALDH1A1IDO1MAOB
SCHEMBL2189373 0.87 RAB9A (0.53) KDM4ERAB9AALDH1A1IDO1MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8308892-B2 Di-cinnamyl compounds and methods for use thereof DESIGNER MOLECULES, INC. (US) 2012-11-13 US claimed
US-20090288768-A1 DI-CINNAMYL COMPOUNDS AND METHODS FOR USE THEREOF DESIGNER MOLECULES, INC. 2009-11-26 US claimed
US-12317892-B2 Micro and nanoparticulate compositions comprising anti-microbially active groups NOBIO LTD. (IL) 2025-06-03 US disclosed
EP-3675801-B1 ANTI-MICROBIAL PARTICLES AND METHODS OF USE THEREOF NOBIO LTD (IL) 2024-01-24 EP disclosed
CN-111093595-B Compositions and medical devices comprising antimicrobial particles 诺比奥有限公司 2023-06-06 CN disclosed
US-20220225612-A1 MICRO AND NANOPARTICULATE COMPOSITIONS COMPRISING ANTI-MICROBIALLY ACTIVE GROUPS NOBIO LTD. (IL) 2022-07-21 US disclosed
US-20220142155-A1 ANTI-MICROBIAL PARTICLES AND METHODS OF USE THEREOF NOBIO LTD. (IL) 2022-05-12 US disclosed
US-20220046915-A1 COMPOSITIONS AND MEDICAL DEVICES COMPRISING ANTI-MICROBIAL PARTICLES NOBIO LTD. (IL) 2022-02-17 US disclosed
US-11178867-B2 Micro and nanoparticulate compositions comprising anti-microbially active groups NOBIO LTD. (IL) 2021-11-23 US disclosed
US-11134676-B2 Anti-microbial particles and methods of use thereof NOBIO LTD. (IL) 2021-10-05 US disclosed
EP-3675802-A1 COMPOSITIONS AND MEDICAL DEVICES COMPRISING ANTI-MICROBIAL PARTICLES Nobio Ltd. (IL) 2020-07-08 EP disclosed
US-8308892-B2 Di-cinnamyl compounds and methods for use thereof DESIGNER MOLECULES, INC. (US) 2012-11-13 US disclosed
EP-1967509-B1 METHOD FOR PRODUCING PRIMARY AMINE COMPOUND SUMITOMO CHEMICAL CO (JP) 2010-04-14 EP disclosed
US-7652170-B2 Method for producing primary amine compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-01-26 US disclosed
US-20090288768-A1 DI-CINNAMYL COMPOUNDS AND METHODS FOR USE THEREOF DESIGNER MOLECULES, INC. 2009-11-26 US disclosed
US-20090287023-A1 METHOD FOR PRODUCING PRIMARY AMINE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-11-19 US disclosed
EP-1967509-A1 METHOD FOR PRODUCING PRIMARY AMINE COMPOUND Sumitomo Chemical Company, Limited (JP) 2008-09-10 EP disclosed
EP-0497202-B1 Polyamine thiols as radioprotective agents MERRELL DOW PHARMA (US) 1995-09-13 EP disclosed
US-5217964-A POLYAMINE THIOLS AS RADIOPROTECTIVE AGENTS MERRELL DOW PHARMACEUTICALS INC. (US) 1993-06-08 US disclosed
EP-0497202-A1 Polyamine thiols as radioprotective agents MERRELL DOW PHARMACEUTICALS INC. (US) 1992-08-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220142155-A1 ANTI-MICROBIAL PARTICLES AND METHODS OF USE THEREOF LPO, MPO, CAPG KDM4E 4003/4885RAB9A 2470/4885ALDH1A1 3866/4885
US-11178867-B2 Micro and nanoparticulate compositions comprising anti-microbially active groups MPO, LPO, DSTN KDM4E 3729/4885RAB9A 593/4885ALDH1A1 3608/4885
US-12317892-B2 Micro and nanoparticulate compositions comprising anti-microbially active groups MPO, LPO, DSTN KDM4E 3729/4885RAB9A 593/4885ALDH1A1 3608/4885
US-20220225612-A1 MICRO AND NANOPARTICULATE COMPOSITIONS COMPRISING ANTI-MICROBIALLY ACTIVE GROUPS MPO, LPO, DSTN KDM4E 3729/4885RAB9A 593/4885ALDH1A1 3608/4885
US-11134676-B2 Anti-microbial particles and methods of use thereof LPO, MPO, CAPG KDM4E 4003/4885RAB9A 2470/4885ALDH1A1 3866/4885
US-20090287023-A1 METHOD FOR PRODUCING PRIMARY AMINE COMPOUND HRH3, HRH4, C5 KDM4E 3624/4885RAB9A 2569/4885ALDH1A1 374/4885
US-20220046915-A1 COMPOSITIONS AND MEDICAL DEVICES COMPRISING ANTI-MICROBIAL PARTICLES CAPG, CD47, CUTA KDM4E 4045/4885RAB9A 2647/4885ALDH1A1 4597/4885
US-20090288768-A1 DI-CINNAMYL COMPOUNDS AND METHODS FOR USE THEREOF CAD, DBF4, ACMSD KDM4E 131/4885RAB9A 4033/4885ALDH1A1 197/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.