SCHEMBL180266

SCHEMBL180266

NC(Cc1c2ccccc2cc2ccccc12)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALPI P09923 1/20 0.55
PKM P14618 1/20 0.55
PTGS1 P23219 1/20 0.55
XIAP P98170 1/20 0.55
SLC7A5 Q01650 1/20 0.55
MEN1 O00255 3/20 0.49
KMT2A Q03164 3/20 0.49
KDM4E B2RXH2 2/20 0.49
MAPT P10636 2/20 0.49
LMNA P02545 1/20 0.49
MPO P05164 1/20 0.49
TSHR P16473 1/20 0.49
BLM P54132 1/20 0.49
PMP22 Q01453 1/20 0.49
HIF1A Q16665 1/20 0.49
HTR2A P28223 1/20 0.48
ALDH1A1 P00352 2/20 0.47
CYP1A2 P05177 1/20 0.47
GLA P06280 1/20 0.47
HPGD P15428 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12434729 1.00 ALPI (0.55) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL887084 1.00 ALPI (0.55) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL29407854 1.00 ALPI (0.55) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL7018652 0.83 SLC7A5 (0.55) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL4456057 0.81 ALPI (0.49) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL12436130 0.80 MAPT (0.54) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL27135549 0.80 MAPT (0.54) ALPIPKMPTGS1XIAPSLC7A5
Hydrochloric Acid SCHEMBL7570495 0.80 ALPI (0.47) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL31485501 0.79 KDM4E (0.49) MEN1KMT2AKDM4EMAPTHTR2A
SCHEMBL31162409 0.79 NOS3 (0.50) ALPIPKMPTGS1XIAPSLC7A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 319 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12521455-B2 Kisspeptin receptor (KISS1R) targeted therapeutics and uses thereof RADIONETICS ONCOLOGY, INC. (US) 2026-01-13 US claimed
US-20250332217-A1 IMMUNE CHECKPOINT INHIBITOR COMBINATIONS LYTIX BIOPHARMA AS (NO) 2025-10-30 US claimed
WO-2025217074-A1 KISSPEPTIN RECEPTOR (KISS1R) TARGETED THERAPEUTICS AND USES THEREOF RADIONETICS ONCOLOGY, INC. (US) 2025-10-16 WO claimed
US-20250312499-A1 KISSPEPTIN RECEPTOR (KISS1R) TARGETED THERAPEUTICS AND USES THEREOF RADIONETICS ONCOLOGY, INC. 2025-10-09 US claimed
EP-4522221-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF NUCLEIC ACID THERAPEUTICS Entrada Therapeutics, Inc. (US) 2025-03-19 EP claimed
US-12239686-B2 Immune checkpoint inhibitor combinations LYTIX BIOPHARMA AS (NO) 2025-03-04 US claimed
US-20240293506-A1 IMMUNE CHECKPOINT INHIBITOR COMBINATIONS LYTIX BIOPHARMA AS (NO) 2024-09-05 US claimed
CN-117915957-A Compositions and methods for modulating mRNA splicing 恩特拉达治疗学股份有限公司 2024-04-19 CN claimed
EP-4337263-A1 COMPOSITIONS AND METHODS FOR MODULATING INTERFERON REGULATORY FACTOR-5 (IRF-5) ACTIVITY Entrada Therapeutics, Inc. (US) 2024-03-20 EP claimed
EP-4337261-A2 COMPOSITIONS AND METHODS FOR MODULATING MRNA SPLICING Entrada Therapeutics, Inc. (US) 2024-03-20 EP claimed
US-20130109834-A1 HIGH SALT-RESISTANCE ANTIBACTERIAL PEPTIDE AND METHOD FOR PRODUCING THE SAME NATIONAL TSING HUA UNIVERSITY (TW) 2013-05-02 US claimed
EP-2297195-B9 ANTIBACTERIAL PEPTIDES SPIDERBIOTECH SRL (IT) 2012-05-09 EP claimed
EP-2402364-A2 A nonapeptide with anti-tumour activity Lytix Biopharma AS (NO) 2012-01-04 EP claimed
US-20110318364-A1 NONAPEPTIDE WITH ANTI-TUMOUR ACTIVITY LYTIX BIOPHARMA AS (NO) 2011-12-29 US claimed
EP-2297195-B1 ANTIBACTERIAL PEPTIDES SPIDERBIOTECH SRL (IT) 2011-11-16 EP claimed
JP-2011521984-A 2011-07-28 JP claimed
US-20110077192-A1 Novel Antibacterial Peptides SPIDERBIOTECH S.R.L. (IT) 2011-03-31 US claimed
EP-2297195-A2 ANTIBACTERIAL PEPTIDES Spiderbiotech S.r.l. (IT) 2011-03-23 EP claimed
WO-2009146886-A2 NOVEL ANTIBACTERIAL PEPTIDES SPIDERBIOTECH S.R.L. (IT) 2009-12-10 WO claimed
US-5658885-A OLIGOPEPTIDES; ANTICOAGULANTS; ENZYME INHIBITORS; THROMBIN THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) 1997-08-19 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110077192-A1 Novel Antibacterial Peptides VIP, NGLY1, NRDC ALPI 3404/4885PKM 4298/4885PTGS1 4002/4885
US-20250312499-A1 KISSPEPTIN RECEPTOR (KISS1R) TARGETED THERAPEUTICS AND USES THEREOF KISS1R, GNRHR, PROKR1 ALPI 3847/4885PKM 1213/4885PTGS1 3753/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.