Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.37 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5958661 | 1.00 | TSHR (0.65) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL5958668 | 1.00 | TSHR (0.65) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL5958681 | 1.00 | TSHR (0.65) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL3195852 | 1.00 | TSHR (0.65) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL40719 | 0.98 | TSHR (0.61) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL40925 | 0.94 | TSHR (0.56) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL27985384 | 0.91 | TSHR (0.59) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL27838291 | 0.89 | TSHR (0.56) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL23002887 | 0.89 | TSHR (0.56) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL5746182 | 0.89 | TSHR (0.56) | TSHRPOLBAPEX1HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2976323-B1 | HIGH REFRACTIVE INDEX ADDITION-FRAGMENTATION AGENTS | 3M INNOVATIVE PROPERTIES CO (US) | 2020-07-15 | — | — | EP | disclosed |
| EP-3259323-B1 | ADDITION-FRAGMENTATION OLIGOMERS | 3M INNOVATIVE PROPERTIES CO (US) | 2020-02-26 | — | — | EP | disclosed |
| EP-2747737-B1 | DENTAL COMPOSITIONS COMPRISING ADDITION-FRAGMENTATION AGENTS | 3M INNOVATIVE PROPERTIES CO (US) | 2019-09-25 | — | — | EP | disclosed |
| US-20190091108-A1 | DENTAL FILLERS, METHODS, AND COMPOSITIONS INCLUDING A PHOSPHATE SALT | 3M INNOVATIVE PROPERTIES CO (US) | 2019-03-28 | — | — | US | disclosed |
| US-10137061-B2 | Dental fillers and compositions including phosphate salts | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2018-11-27 | — | — | US | disclosed |
| EP-2931756-B1 | ADDITION-FRAGMENTATION OLIGOMERS | 3M INNOVATIVE PROPERTIES CO (US) | 2018-08-08 | — | — | EP | disclosed |
| EP-3058014-B1 | ALLYL DISULFIDE-CONTAINING ADDITION-FRAGMENTATION OLIGOMERS | 3M INNOVATIVE PROPERTIES CO (US) | 2018-06-20 | — | — | EP | disclosed |
| EP-3046962-B1 | TRITHIOCARBONATE-CONTAINING ADDITION-FRAGMENTATION AGENTS | 3M INNOVATIVE PROPERTIES CO (US) | 2018-05-23 | — | — | EP | disclosed |
| EP-3259323-A1 | ADDITION-FRAGMENTATION OLIGOMERS | 3M Innovative Properties Company (US) | 2017-12-27 | — | — | EP | disclosed |
| US-9758478-B2 | Allyl disulfide-containing addition-fragmentation oligomers | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2017-09-12 | — | — | US | disclosed |
| EP-1819313-A1 | DENTAL FILLERS AND COMPOSITIONS INCLUDING PHOSPHATE SALTS | 3M Innovative Properties Company (US) | 2007-08-22 | — | — | EP | disclosed |
| EP-1811944-A1 | DENTAL FILLERS, METHODS, COMPOSITIONS INCLUDING A CASEINATE | 3M Innovative Properties Company (US) | 2007-08-01 | — | — | EP | disclosed |
| EP-1811942-A1 | DENTAL COMPOSITIONS WITH CALCIUM PHOSPHORUS RELEASING GLASS | 3M Innovative Properties Company (US) | 2007-08-01 | — | — | EP | disclosed |
| WO-2006098882-A1 | HARDENABLE ANTIMICROBIAL DENTAL COMPOSITIONS AND METHODS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2006-09-21 | — | — | WO | disclosed |
| US-20060205838-A1 | Hardenable antimicrobial dental compositions and methods | 3M INNOVATIVE PROPERTIES COMPANY | 2006-09-14 | — | — | US | disclosed |
| WO-2006055329-A2 | DENTAL FILLERS INCLUDING A PHOSPHORUS-CONTAINING SURFACE TREATMENT | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2006-05-26 | — | — | WO | disclosed |
| WO-2006055328-A1 | DENTAL FILLERS, METHODS, COMPOSITIONS INCLUDING A CASEINATE | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2006-05-26 | — | — | WO | disclosed |
| WO-2006055317-A1 | DENTAL COMPOSITIONS WITH CALCIUM PHOSPHORUS RELEASING GLASS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2006-05-26 | — | — | WO | disclosed |
| WO-2006055327-A1 | DENTAL FILLERS AND COMPOSITIONS INCLUDING PHOSPHATE SALTS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2006-05-26 | — | — | WO | disclosed |
| CN-1310720-A | Organophosphorus compounds for dental polymerizable compositions | KURARAY CO (JP) | 2001-08-29 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060205838-A1 | Hardenable antimicrobial dental compositions and methods | PLIN3, LIPA, PHOSPHO1 | TSHR 4480/4885POLB 419/4885APEX1 103/4885 |
| US-20190091108-A1 | DENTAL FILLERS, METHODS, AND COMPOSITIONS INCLUDING A PHOSPHATE SALT | CD44, PPA1, RPN1 | TSHR 3498/4885POLB 1418/4885APEX1 1518/4885 |
| US-10137061-B2 | Dental fillers and compositions including phosphate salts | PPA1, RPN1, DCPS | TSHR 3696/4885POLB 1292/4885APEX1 1353/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.