Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.61 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.34 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5958668 | 0.98 | TSHR (0.65) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL5958681 | 0.98 | TSHR (0.65) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL5958661 | 0.98 | TSHR (0.65) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL3195852 | 0.98 | TSHR (0.65) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL180279 | 0.98 | TSHR (0.65) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL40925 | 0.96 | TSHR (0.56) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL27838291 | 0.91 | TSHR (0.56) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL27985384 | 0.90 | TSHR (0.59) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL3690714 | 0.90 | TSHR (0.54) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL41530 | 0.88 | THRB (0.57) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4746543-B2 | — | — | 2011-08-10 | — | — | JP | claimed |
| US-7700668-B2 | Adhesive composition with decreased polarity upon polymerization | 3M ESPE AG (DE) | 2010-04-20 | — | — | US | claimed |
| US-20060270751-A1 | Adhesive composition with decreased polarity upon polymerization | 3M DEUTSCHLAND GMBH (DE) | 2006-11-30 | — | — | US | claimed |
| EP-1498098-B1 | Adhesive composition with decreased polarity upon polymerization | 3M ESPE AG (DE) | 2006-05-03 | — | — | EP | claimed |
| WO-2005004819-A1 | ADHESIVE COMPOSITION WITH DECREASED POLARITY UPON POLYMERIZATION | 3M ESPE AG (DE) | 2005-01-20 | — | — | WO | claimed |
| EP-1498098-A1 | Adhesive composition with decreased polarity upon polymerization | 3M ESPE AG (DE) | 2005-01-19 | — | — | EP | claimed |
| WO-2021116678-A1 | IMPROVEMENTS IN, OR RELATING TO, BINDERS AND/OR COATINGS | SYNTHOMER (UK) LIMITED (GB) | 2021-06-17 | — | — | WO | disclosed |
| US-10711073-B2 | Method of making a branched polymer, a branched polymer and uses of such a polymer | SYNTHOMER (UK) LIMITED (GB) | 2020-07-14 | — | — | US | disclosed |
| US-10584263-B2 | Aqueous polymer-silicon oil hybrid composition | BASF SE (DE) | 2020-03-10 | — | — | US | disclosed |
| EP-3434698-A1 | METHOD OF MAKING A BRANCHED POLYMER, A BRANCHED POLYMER AND USES OF SUCH A POLYMER | Synthomer (UK) Ltd. (GB) | 2019-01-30 | — | — | EP | disclosed |
| EP-3119815-B1 | METHOD OF MAKING A BRANCHED POLYMER, A BRANCHED POLYMER AND USES OF SUCH A POLYMER | SYNTHOMER UK LTD (GB) | 2018-06-20 | — | — | EP | disclosed |
| US-20170247570-A1 | AQUEOUS POLYMER-SILICON OIL HYBRID COMPOSITION | BASF SE (DE) | 2017-08-31 | — | — | US | disclosed |
| EP-3197923-A1 | AQUEOUS POLYMER-SILICON OIL HYBRID COMPOSITION | BASF SE (DE) | 2017-08-02 | — | — | EP | disclosed |
| US-20060270751-A1 | Adhesive composition with decreased polarity upon polymerization | 3M DEUTSCHLAND GMBH (DE) | 2006-11-30 | — | — | US | disclosed |
| EP-1498098-B1 | Adhesive composition with decreased polarity upon polymerization | 3M ESPE AG (DE) | 2006-05-03 | — | — | EP | disclosed |
| US-20060069181-A1 | Dental adhesive composition | 3M ESPE AG | 2006-03-30 | — | — | US | disclosed |
| EP-1639987-A1 | Dental adhesive composition | 3M Espe AG (DE) | 2006-03-29 | — | — | EP | disclosed |
| WO-2005004819-A1 | ADHESIVE COMPOSITION WITH DECREASED POLARITY UPON POLYMERIZATION | 3M ESPE AG (DE) | 2005-01-20 | — | — | WO | disclosed |
| EP-1498098-A1 | Adhesive composition with decreased polarity upon polymerization | 3M ESPE AG (DE) | 2005-01-19 | — | — | EP | disclosed |
| US-4576793-A | MULTILAYER, POROSITY, SPREADING, UNSATURATED ACID COPOLYMEWR | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1986-03-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060270751-A1 | Adhesive composition with decreased polarity upon polymerization | PTK2, PHOSPHO1, ITGA1 | TSHR 4650/4885THRB 3495/4885POLB 868/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.