Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22106078 | 0.95 | THRB (0.69) | THRBTHRA | |
| SCHEMBL30762940 | 0.93 | THRB (0.69) | THRBTHRA | |
| SCHEMBL22095558 | 0.93 | THRB (0.69) | THRBTHRA | |
| SCHEMBL18028276 | 0.92 | THRB (0.72) | THRBTHRA | |
| SCHEMBL22106058 | 0.92 | THRB (0.66) | THRBTHRA | |
| SCHEMBL22095708 | 0.90 | THRB (0.63) | THRBTHRA | |
| SCHEMBL22106244 | 0.90 | THRB (0.63) | THRBTHRA | |
| SCHEMBL22106149 | 0.90 | THRB (0.63) | THRBTHRA | |
| SCHEMBL18028281 | 0.89 | THRB (0.71) | THRBTHRA | |
| SCHEMBL18028289 | 0.89 | THRB (0.71) | THRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200361849-A1 | NOVEL THYROMIMETICS | AUTOBAHN THERAPEUTICS, INC. | 2020-11-19 | — | — | US | disclosed |
| WO-2020123861-A1 | NOVEL THYROMIMETICS | AUTOBAHN THERAPEUTICS, INC. (US) | 2020-06-18 | — | — | WO | disclosed |
| US-20200181103-A1 | DERIVATIVES OF SOBETIROME | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2020-06-11 | — | — | US | disclosed |
| US-10392356-B2 | Derivatives of sobetirome | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2019-08-27 | — | — | US | disclosed |
| US-20180057472-A1 | DERIVATIVES OF SOBETIROME | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2018-03-01 | — | — | US | disclosed |
| US-20180057472-A1 | DERIVATIVES OF SOBETIROME | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2018-03-01 | — | — | US | disclosed |
| US-9701650-B2 | Derivatives of sobetirome | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2017-07-11 | — | — | US | disclosed |
| US-9701650-B2 | Derivatives of sobetirome | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2017-07-11 | — | — | US | disclosed |
| WO-2016134292-A1 | DERIVATIVES OF SOBETIROME | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2016-08-25 | — | — | WO | disclosed |
| US-20160244418-A1 | DERIVATIVES OF SOBETIROME | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2016-08-25 | — | — | US | disclosed |
| US-20160244418-A1 | DERIVATIVES OF SOBETIROME | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2016-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200181103-A1 | DERIVATIVES OF SOBETIROME | SLC18A2, SLC6A2, SLC6A4 | THRB 1531/4885THRA 2065/4885 |
| US-20200361849-A1 | NOVEL THYROMIMETICS | TPO, THOP1, TSHR | THRB 12/4885THRA 9/4885 |
| US-20180057472-A1 | DERIVATIVES OF SOBETIROME | SLC18A2, SLC6A2, SLC6A4 | THRB 1531/4885THRA 2065/4885 |
| US-20160244418-A1 | DERIVATIVES OF SOBETIROME | SLC18A2, SLC6A2, SLC6A4 | THRB 1531/4885THRA 2065/4885 |
| US-10392356-B2 | Derivatives of sobetirome | SLC18A2, SLC6A2, SLC6A4 | THRB 1531/4885THRA 2065/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.