Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.46 |
| ▸ | NQO2 | P16083 | 1/20 | 0.46 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18028919 | 0.90 | ADRB2 (0.59) | ALDH1A1MAPTRECQLADRB2MTNR1A | |
| SCHEMBL18029123 | 0.83 | MAPT (0.52) | ALDH1A1MAPTRECQLMEN1KMT2A | |
| SCHEMBL18029329 | 0.83 | MAPT (0.52) | ALDH1A1MAPTRECQLMEN1KMT2A | |
| SCHEMBL18029250 | 0.83 | MAPT (0.52) | ALDH1A1MAPTRECQLMEN1KMT2A | |
| SCHEMBL19871244 | 0.82 | MAPT (0.51) | ALDH1A1MAPTRECQLMEN1KMT2A | |
| SCHEMBL18029133 | 0.82 | MAPT (0.51) | ALDH1A1MAPTRECQLMEN1KMT2A | |
| SCHEMBL19871241 | 0.82 | ALDH1A1 (0.51) | ALDH1A1MAPTRECQLMEN1KMT2A | |
| SCHEMBL18029076 | 0.81 | MAPT (0.50) | ALDH1A1MAPTRECQLMEN1KMT2A | |
| SCHEMBL19871246 | 0.80 | MAPT (0.55) | ALDH1A1MAPTRECQLMEN1KMT2A | |
| SCHEMBL7254162 | 0.80 | HTR6 (0.63) | ALDH1A1MAPTRECQLHTR6MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016134145-A9 | ARTIFICIAL SELF-SUFFICIENT CYTOCHROME P450S | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2017-02-16 | — | — | WO | disclosed |
| WO-2016134145-A2 | ARTIFICIAL SELF-SUFFICIENT CYTOCHROME P450S | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2016-08-25 | — | — | WO | disclosed |