Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | IDH2 | P48735 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25974193 | 0.74 | IDH2 (0.50) | HPGDATML3MBTL1HSD17B10MAPT | |
| SCHEMBL18007531 | 0.72 | MAPT (0.46) | MAPTMEN1ALDH1A1KMT2AKDM4E | |
| SCHEMBL12579013 | 0.70 | HSD17B10 (0.45) | HSD17B10KDM4ETSHRHMGCR | |
| SCHEMBL173244 | 0.70 | HMGCR (0.46) | HSD17B10KDM4EHMGCR | |
| SCHEMBL21586573 | 0.70 | HSD17B10 (0.37) | HPGDHSD17B10KDM4ETSHRHMGCR | |
| SCHEMBL18007575 | 0.69 | HSD17B10 (0.72) | L3MBTL1HSD17B10MAPTKDM4E | |
| SCHEMBL12257760 | 0.69 | HRH4 (0.53) | HPGDL3MBTL1HSD17B10MAPTMEN1 | |
| SCHEMBL26777976 | 0.69 | NOS3 (0.38) | HSD17B10KDM4EHMGCR | |
| SCHEMBL26739799 | 0.69 | NOS3 (0.38) | HPGDL3MBTL1HSD17B10MAPTALDH1A1 | |
| SCHEMBL25846980 | 0.69 | NOS3 (0.42) | HSD17B10MAPTALDH1A1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3888749-A1 | SULFONYLUREAS AND RELATED COMPOUNDS AND USE OF SAME | The University of Queensland (AU) | 2021-10-06 | — | — | EP | disclosed |
| WO-2016131098-A1 | SULFONYLUREAS AND RELATED COMPOUNDS AND USE OF SAME | THE UNIVERSITY OF QUEENSLAND (AU) | 2016-08-25 | — | — | WO | disclosed |