Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 5/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26022486 | 0.88 | HSP90AA1 (0.41) | HMGCRHSD17B10KDM4E | |
| SCHEMBL12257766 | 0.85 | KDM4E (0.39) | HMGCRHSD17B10KDM4EHRH4 | |
| SCHEMBL19051434 | 0.83 | HSD17B10 (0.42) | HMGCRHSD17B10KDM4EHRH4 | |
| SCHEMBL6181050 | 0.83 | HMGCR (0.37) | HMGCRHSD17B10KDM4E | |
| SCHEMBL26020405 | 0.83 | HMGCR (0.37) | HMGCRHSD17B10KDM4E | |
| SCHEMBL13807433 | 0.83 | HMGCR (0.37) | HMGCRHSD17B10KDM4E | |
| SCHEMBL7255653 | 0.83 | HMGCR (0.37) | HMGCRHSD17B10KDM4EHRH4 | |
| SCHEMBL13812332 | 0.79 | HMGCR (0.49) | HMGCRHSD17B10KDM4E | |
| SCHEMBL16259689 | 0.79 | HMGCR (0.42) | HMGCRHSD17B10 | |
| SCHEMBL21341304 | 0.79 | HSD17B10 (0.40) | HMGCRHSD17B10KDM4EHRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 176 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118930484-A | Synthesis method for stereoselectively constructing cis-or trans-benzohydrogenated isoquinoline | 兰州大学 | 2024-11-12 | — | — | CN | claimed |
| CN-115232177-B | Chemical synthesis method of shigella dysenteriae 10 type O-antigen oligosaccharide | 江南大学 | 2024-07-30 | — | — | CN | claimed |
| CN-118184718-A | Aspergillus fumigatus furan galactomannan-oligosaccharide derivative and preparation method and application thereof | 山东大学 | 2024-06-14 | — | — | CN | claimed |
| US-20240117115-A1 | POLY(CYCLIC ACETAL)S, METHODS OF MAKING SAME, AND USES THEREOF | U.S. DEPARTMENT OF ENERGY | 2024-04-11 | — | — | US | claimed |
| CN-114604848-B | Nitrogen-rich graphdiyne and preparation method thereof | 武汉工程大学 | 2023-03-21 | — | — | CN | claimed |
| CN-115232177-A | Chemical synthesis method of shigella dysenteriae type 10O-antigen oligosaccharide | 江南大学 | 2022-10-25 | — | — | CN | claimed |
| WO-2022182415-A1 | HIMASTATIN DERIVATIVES, AND PROCESSES OF PREPARATION THEREOF, AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2022-09-01 | — | — | WO | claimed |
| WO-2022159777-A1 | POLY(CYCLIC ACETAL)S, METHODS OF MAKING SAME, AND USES THEREOF | CORNELL UNIVERSITY (US) | 2022-07-28 | — | — | WO | claimed |
| CN-114478659-B | Preparation method of disaccharide compound | 启德医药科技（苏州）有限公司 | 2022-07-15 | — | — | CN | claimed |
| CN-114604848-A | Nitrogen-rich graphdiyne and preparation method thereof | 武汉工程大学 | 2022-06-10 | — | — | CN | claimed |
| US-9422325-B2 | Glycosylation reactions using phenyl(trifluoroethyl)iodonium salts | TRUSTEES OF TUFTS COLLEGE (US) | 2016-08-23 | — | — | US | claimed |
| US-20150099870-A1 | Glycosylation Reactions Using Phenyl(trifluoroethyl)iodonium Salts | TRUSTEES OF TUFTS COLLEGE | 2015-04-09 | — | — | US | claimed |
| US-8257493-B2 | Photonic crystal, conjugated polymers suitable for photonic crystal, and a method for synthesizing conjugated polymers | THE UNIVERSITY OF AKRON (US) | 2012-09-04 | — | — | US | claimed |
| US-20080130111-A1 | Photonic Crystal, Conjugated Polymers Suitable for Photonic Crystal, and a Method for Synthesizing Conjugated Polymers | AKRON, UNIVERSITY OF | 2008-06-05 | — | — | US | claimed |
| WO-2006131616-A1 | NEW TYPE OF MOLECULAR JUNCTION BETWEEN A SEMICONDUCTOR AND A METAL | MICHELET DANIEL (FR) | 2006-12-14 | — | — | WO | claimed |
| US-6960654-B2 | Method of forming glycosidic bonds from thioglycosides using an N,N-dialkylsulfinamide | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2005-11-01 | — | — | US | claimed |
| US-6930187-B2 | Method of preparation of 21-amino epothilone derivatives | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-08-16 | — | — | US | claimed |
| US-20040019198-A1 | Method of forming glycosidic bonds from thioglycosides using an N,N-dialkylsulfinamide | CRICH DAVID C (US) | 2004-01-29 | — | — | US | claimed |
| US-20030187039-A1 | Method of preparation of 21-amino epothilone derivatives | INVENSYS SYSTEMS, INC. | 2003-10-02 | — | — | US | claimed |
| WO-2003070170-A2 | METHOD OF PREPARATION OF 21-AMINO EPOTHILONE DERIVATIVES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-08-28 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150099870-A1 | Glycosylation Reactions Using Phenyl(trifluoroethyl)iodonium Salts | UGGT1, OGA, GPI | HMGCR 3559/4885HSD17B10 2056/4885KDM4E 2745/4885 |
| US-20030187039-A1 | Method of preparation of 21-amino epothilone derivatives | DHPS, CYP17A1, HSD17B7 | HMGCR 273/4885HSD17B10 122/4885KDM4E 2278/4885 |
| US-20240117115-A1 | POLY(CYCLIC ACETAL)S, METHODS OF MAKING SAME, AND USES THEREOF | CD38, ADCY1, ADCY2 | HMGCR 4493/4885HSD17B10 2197/4885KDM4E 1085/4885 |
| US-20040019198-A1 | Method of forming glycosidic bonds from thioglycosides using an N,N-dialkylsulfinamide | DDOST, STT3B, STT3A | HMGCR 4137/4885HSD17B10 3081/4885KDM4E 4592/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.