Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | HMGCR | P04035 | 5/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24133940 | 0.81 | HSP90AA1 (0.38) | HSD17B10HPGDTSHRKDM4E | |
| SCHEMBL19871662 | 0.75 | HSD17B10 (0.41) | HSD17B10HMGCRKDM4E | |
| SCHEMBL21341471 | 0.72 | HMGCR (0.46) | HSD17B10HMGCR | |
| SCHEMBL17789406 | 0.71 | HSP90AA1 (0.50) | HSD17B10HPGDTSHRKDM4E | |
| SCHEMBL12092561 | 0.70 | HTT (0.43) | TSHRKDM4E | |
| SCHEMBL18029620 | 0.70 | HPGD (0.42) | HSD17B10HMGCRHPGDTSHRKDM4E | |
| SCHEMBL21341345 | 0.69 | HMGCR (0.34) | HMGCR | |
| SCHEMBL12579013 | 0.66 | HSD17B10 (0.45) | HSD17B10HMGCRTSHRKDM4E | |
| SCHEMBL173244 | 0.66 | HMGCR (0.46) | HSD17B10HMGCRKDM4E | |
| SCHEMBL23613212 | 0.65 | ALDH1A1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3578547-A1 | SULFONYLUREAS AND RELATED COMPOUNDS AND USE OF SAME | The University of Queensland (AU) | 2019-12-11 | — | — | EP | disclosed |