Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 2/20 | 0.34 |
| ▸ | CFTR | P13569 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.34 |
| ▸ | FPR2 | P25090 | 4/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.32 |
| ▸ | IGLV6-57 | P01721 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | SCN1A | P35498 | 1/20 | 0.31 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16405434 | 0.88 | TGM2 (0.46) | TGM2USP2FPR2CHRM1MEN1 | |
| SCHEMBL18027490 | 0.88 | TGM2 (0.46) | TGM2USP2FPR2CHRM1MEN1 | |
| SCHEMBL2732905 | 0.85 | ABCB1 (0.43) | TGM2ABCB1USP2ATMCFTR | |
| SCHEMBL22851948 | 0.83 | MAOB (0.45) | TGM2ABCB1USP2ATMCFTR | |
| SCHEMBL18840607 | 0.83 | TGM2 (0.37) | TGM2ABCB1USP2ATMCFTR | |
| SCHEMBL20961733 | 0.81 | ABCB1 (0.40) | TGM2ABCB1USP2ATMCFTR | |
| SCHEMBL15100480 | 0.79 | ABCB1 (0.53) | TGM2ABCB1USP2ATMCFTR | |
| SCHEMBL14338981 | 0.78 | TGM2 (0.46) | TGM2USP2FPR2CHRM1MEN1 | |
| SCHEMBL14339025 | 0.78 | TGM2 (0.41) | TGM2ABCB1USP2ATMCFTR | |
| SCHEMBL15100483 | 0.77 | TGM2 (0.42) | TGM2ABCB1USP2ATMCFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9744180-B2 | Pharmaceutical formulations containing mitochondrially targeted antioxidants | MITOTECH SA (LU) | 2017-08-29 | — | — | US | disclosed |
| US-20160243136-A1 | PHARMACEUTICAL FORMULATIONS CONTAINING MITOCHONDRIALLY TARGETED ANTIOXIDANTS | ESSEX BIO-INVESTMENT LIMITED (HK) | 2016-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160243136-A1 | PHARMACEUTICAL FORMULATIONS CONTAINING MITOCHONDRIALLY TARGETED ANTIOXIDANTS | TXNRD2, TXN2, GSR | TGM2 644/4885ABCB1 798/4885USP2 3397/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.