Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JUN | P05412 | 1/20 | 0.57 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29709940 | 0.86 | JUN (0.78) | JUNSTAT3 | |
| SCHEMBL18034513 | 0.82 | JUN (0.54) | JUN | |
| Yukonin SCHEMBL7493922 | 0.68 | JUN (0.70) | JUN | |
| SCHEMBL18034641 | 0.66 | STAT3 (0.52) | JUNSTAT3 | |
| SCHEMBL7974137 | 0.61 | JUN (0.67) | JUN | |
| SCHEMBL7497165 | 0.61 | JUN (0.67) | JUN | |
| SCHEMBL18034495 | 0.56 | LMNA (0.60) | — | |
| SCHEMBL20045268 | 0.50 | JUN (0.37) | JUN | |
| SCHEMBL19140901 | 0.49 | JUN (0.36) | JUN | |
| SCHEMBL13778139 | 0.49 | MAPT (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016131426-A1 | NAGILACTONE COMPOUNDS HAVING ANTILIPEMIC ACTIVITY, PREPARATION METHOD THEREFOR AND USES THEREOF | 中国科学院上海药物研究所 | 2016-08-25 | — | — | WO | disclosed |