Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.52 |
| ▸ | JUN | P05412 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MITF | O75030 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29709891 | 0.83 | JUN (0.52) | STAT3JUN | |
| SCHEMBL18034517 | 0.66 | JUN (0.57) | STAT3JUN | |
| SCHEMBL18034495 | 0.61 | LMNA (0.60) | NPC1MITFLMNANFKB1HTT | |
| SCHEMBL18034509 | 0.57 | LMNA (0.74) | NPC1MITFLMNANFKB1HTT | |
| SCHEMBL18034519 | 0.56 | JUN (0.40) | STAT3JUN | |
| SCHEMBL7922761 | 0.55 | JUN (0.39) | JUNLMNAHTTSMN1; SMN2 | |
| SCHEMBL29709940 | 0.54 | JUN (0.78) | STAT3JUN | |
| SCHEMBL11989123 | 0.50 | MGAM (0.31) | NPC1MITFLMNANFKB1HTT | |
| Loliolide SCHEMBL16057196 | 0.50 | ACHE (0.53) | STAT3 | |
| SCHEMBL12464454 | 0.48 | HIF1A (0.33) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016131426-A1 | NAGILACTONE COMPOUNDS HAVING ANTILIPEMIC ACTIVITY, PREPARATION METHOD THEREFOR AND USES THEREOF | 中国科学院上海药物研究所 | 2016-08-25 | — | — | WO | disclosed |