Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 2/20 | 0.35 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.35 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | CTSA | P10619 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18036425 | 1.00 | P2RX3 (0.35) | P2RX3P2RX2MAP3K5FAAHPTGS2 | |
| SCHEMBL18036399 | 0.92 | APOL1 (0.34) | FAAHPTGS2 | |
| SCHEMBL18036393 | 0.92 | P2RX3 (0.43) | P2RX3P2RX2MAP3K5FAAHCTSA | |
| SCHEMBL18036415 | 0.91 | HPGD (0.35) | FAAHPTGS2 | |
| SCHEMBL18036447 | 0.91 | HPGD (0.35) | FAAHPTGS2 | |
| SCHEMBL18036373 | 0.90 | DGAT2 (0.32) | — | |
| SCHEMBL18036395 | 0.89 | P2RX3 (0.41) | P2RX3P2RX2 | |
| SCHEMBL18036402 | 0.89 | P2RX3 (0.41) | P2RX3P2RX2 | |
| SCHEMBL18036356 | 0.88 | P2RX3 (0.40) | P2RX3P2RX2 | |
| SCHEMBL10244247 | 0.87 | P2RX3 (0.47) | P2RX3P2RX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2592070-B1 | Tetrazole-substituted arylamides | HOFFMANN LA ROCHE (CH) | 2016-08-31 | — | — | EP | claimed |