Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.34 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.33 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | EED | O75530 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL17940839 | 0.92 | L3MBTL1 (0.32) | ROCK1JAK2JAK3PTK2L3MBTL1 | |
| Hydrochloric Acid SCHEMBL19453222 | 0.86 | ROCK1 (0.30) | ROCK1 | |
| SCHEMBL17169025 | 0.80 | MEN1 (0.38) | ROCK1JAK2JAK3PTK2NUDT1 | |
| SCHEMBL17171843 | 0.80 | MEN1 (0.40) | ROCK1JAK2JAK3PTK2NUDT1 | |
| SCHEMBL17952987 | 0.78 | JAK2 (0.38) | ROCK1JAK2JAK3PTK2NUDT1 | |
| SCHEMBL19337843 | 0.78 | ROCK1 (0.37) | ROCK1JAK2JAK3PTK2NUDT1 | |
| SCHEMBL17022600 | 0.78 | ROCK1 (0.34) | ROCK1JAK2JAK3PTK2NUDT1 | |
| Hydrochloric Acid SCHEMBL18036615 | 0.78 | ROCK1 (0.39) | ROCK1JAK2JAK3PTK2NUDT1 | |
| SCHEMBL17022705 | 0.77 | MEN1 (0.34) | ROCK1JAK2JAK3PTK2NUDT1 | |
| SCHEMBL17022510 | 0.77 | ROCK1 (0.39) | ROCK1JAK2JAK3PTK2NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9828450-B2 | Propylene-based elastomer | LG CHEM, LTD. (KR) | 2017-11-28 | — | — | US | disclosed |
| US-20160251461-A1 | PROPYLENE-BASED ELASTOMER | LG CHEM, LTD. (KR) | 2016-09-01 | — | — | US | disclosed |