Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.35 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17169025 | 0.98 | MEN1 (0.38) | JAK2JAK3PTK2MEN1KMT2A | |
| SCHEMBL17169024 | 0.95 | SMN1; SMN2 (0.39) | MEN1KMT2AALDH1A1SMN1; SMN2ROCK1 | |
| SCHEMBL17952983 | 0.89 | L3MBTL1 (0.35) | JAK2JAK3PTK2MEN1KMT2A | |
| SCHEMBL17952989 | 0.87 | CHRM2 (0.35) | JAK2JAK3PTK2MEN1KMT2A | |
| SCHEMBL17952988 | 0.87 | ROCK1 (0.34) | JAK2JAK3PTK2MEN1KMT2A | |
| SCHEMBL17952985 | 0.86 | DRD2 (0.34) | SMN1; SMN2SRD5A1 | |
| SCHEMBL17952984 | 0.86 | CHRM2 (0.34) | JAK2JAK3PTK2MEN1KMT2A | |
| SCHEMBL17952995 | 0.85 | ROCK1 (0.35) | MEN1KMT2AALDH1A1SMN1; SMN2ROCK1 | |
| SCHEMBL17952996 | 0.85 | CHRM2 (0.34) | MEN1KMT2AALDH1A1SMN1; SMN2SRD5A1 | |
| SCHEMBL17952990 | 0.84 | SMN1; SMN2 (0.34) | MEN1KMT2AALDH1A1SMN1; SMN2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9790240-B2 | Ligand compound, a preparation method thereof, a transition metal compound, and a preparation method thereof | LG CHEM, LTD. (KR) | 2017-10-17 | — | — | US | disclosed |
| US-20160215004-A1 | A NOVEL LIGAND COMPOUND, A PREPARATION METHOD THEREOF, A TRANSITION METAL COMPOUND, AND A PREPARATION METHOD THEREOF | LG CHEM, LTD. (KR) | 2016-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160215004-A1 | A NOVEL LIGAND COMPOUND, A PREPARATION METHOD THEREOF, A TRANSITION METAL COMPOUND, AND A PREPARATION METHOD THEREOF | CD40LG, OSTC, TNFSF10 | JAK2 980/4885JAK3 2606/4885PTK2 1186/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.