Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 1/20 | 0.46 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | METAP2 | P50579 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4452379 | 0.78 | CA2 (0.53) | ALDH1A1KDM4EHPGDMAPTTSHR | |
| SCHEMBL8579469 | 0.77 | ALDH1A1 (0.54) | CTNNB1BCAT2ALDH1A1KDM4EHPGD | |
| SCHEMBL1415250 | 0.77 | ALDH1A1 (0.54) | CTNNB1BCAT2ALDH1A1KDM4EHPGD | |
| SCHEMBL5445179 | 0.76 | BCAT2 (0.48) | CTNNB1BCAT2ALDH1A1KDM4EHPGD | |
| SCHEMBL4596579 | 0.75 | ALDH1A1 (0.52) | CTNNB1BCAT2ALDH1A1KDM4EHPGD | |
| SCHEMBL1003855 | 0.75 | TRIM24 (0.54) | CTNNB1BCAT2ALDH1A1KDM4EHPGD | |
| SCHEMBL1515606 | 0.75 | ALDH1A1 (0.52) | CTNNB1BCAT2ALDH1A1KDM4EHPGD | |
| SCHEMBL770829 | 0.74 | BCAT2 (0.52) | CTNNB1BCAT2ALDH1A1KDM4EHPGD | |
| SCHEMBL1004375 | 0.74 | ALDH1A1 (0.50) | CTNNB1BCAT2ALDH1A1KDM4EHPGD | |
| SCHEMBL1829025 | 0.74 | ALDH1A1 (0.50) | CTNNB1BCAT2ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10358651-B2 | Modified plants and methods for producing modified lignin by modulating expression of acyltransferases | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2019-07-23 | — | — | US | disclosed |
| US-20160251672-A1 | Modified plants and methods for producing modified lignin by modulating expression of acyltransferases | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-09-01 | — | — | US | disclosed |