SCHEMBL180385

SCHEMBL180385

Nc1ccc(C(=O)O)cc1O

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.64
MAPT P10636 5/20 0.64
GAA P10253 5/20 0.64
CA12 O43570 4/20 0.64
CA1 P00915 4/20 0.64
CA2 P00918 4/20 0.64
CA6 P23280 4/20 0.64
CA9 Q16790 4/20 0.64
CA4 P22748 3/20 0.64
CA7 P43166 3/20 0.64
CA14 Q9ULX7 3/20 0.64
POLB P06746 2/20 0.64
PTGS2 P35354 1/20 0.64
L3MBTL1 Q9Y468 1/20 0.64
CDC25B P30305 1/20 0.57
LMNA P02545 2/20 0.53
HSD17B10 Q99714 4/20 0.50
ALDH1A1 P00352 3/20 0.50
HPGD P15428 3/20 0.50
TP53 P04637 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9797575 0.98 MAPT (0.61) KDM4EMAPTGAACA12CA1
SCHEMBL9306191 0.98 KDM4E (0.61) KDM4EMAPTGAACA12CA1
Phosphoric Acid SCHEMBL9468960 0.92 KDM4E (0.55) KDM4EMAPTGAACA12CA1
Aniline SCHEMBL7897579 0.90 KDM4E (0.53) KDM4EMAPTGAACA12CA1
SCHEMBL10434120 0.89 MAPT (0.52) KDM4EMAPTGAACA12CA1
SCHEMBL9328747 0.88 SRD5A2 (0.58) KDM4EMAPTGAACA12CA1
SCHEMBL29412590 0.84 HSD17B10 (0.52) KDM4EMAPTGAACA12CA1
SCHEMBL766129 0.84 HSD17B10 (0.52) KDM4EMAPTGAACA12CA1
SCHEMBL2404415 0.84 HSD17B10 (0.65) KDM4ECA12CA1CA2CA9
Hydrochloric Acid SCHEMBL17559530 0.82 HSD17B10 (0.63) KDM4ECA12CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2048 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12637701-B2 Transformed cell having ability to produce 2,5-pyridine dicarboxylic acid KAO CORPORATION (JP) 2026-05-26 US claimed
EP-4077287-B1 EFFICIENT PROCESS FOR MAKING 6-CARBOXY BENZOXAZOLE DERIVATIVES PFIZER IRELAND PHARMACEUTICALS UNLIMITED COMPANY (IE) 2025-11-19 EP claimed
WO-2025085689-A1 EXTRACELLULAR SMALL MOLECULE ACTIVATORS TARGETING BESTROPHIN CHANNELS FOR DISEASE TREATMENT THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2025-04-24 WO claimed
CN-119833264-A Preparation process of high-performance composite porcelain suspension rod insulator 江西百新电瓷电气有限公司 2025-04-15 CN claimed
CN-115135639-B Efficient process for preparing 6-carboxybenzoxazole derivatives 辉瑞爱尔兰制药公司 2025-04-01 CN claimed
CN-119384512-A Method for producing aromatic compound 花王株式会社 2025-01-28 CN claimed
CN-114907283-B Preparation method of 2- (3, 5-dichlorophenyl) -benzoxazole-6-carboxylic acid 南京正大天晴制药有限公司 2025-01-28 CN claimed
US-20250019728-A1 METHOD FOR PRODUCING AROMATIC COMPOUND KAO CORPORATION (JP) 2025-01-16 US claimed
CN-119243479-A Microfiber spinning oil and preparation method thereof 上海鑫妙纺织助剂有限公司 2025-01-03 CN claimed
CN-118909556-B Self-adhesive coiled material for repairing concrete pavement and preparation method thereof 湖南盛业土工材料制造有限公司 2024-12-24 CN claimed
EP-0615998-A2 Synthesis of aromatic heterocyclic polymers from a biosynthetically prepared precursor GENERAL ELECTRIC COMPANY (US) 1994-09-21 EP claimed
US-5340913-A Synthesis of aromatic heterocyclic polymers from a biosynthetically prepared precursor GENERAL ELECTRIC COMPANY (US) 1994-08-23 US claimed
US-5223373-A Positive working photosensitive composition and photosensitive electrodeposition composition prepared therefrom INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 1993-06-29 US claimed
US-5219981-A Semi-continuous process for synthesis of polybenzazole polymers THE DOW CHEMICAL COMPANY (US) 1993-06-15 US claimed
WO-1993010677-A1 SPECIFIC EATABLE TASTE MODIFIERS BIORESEARCH, INC. (US) 1993-06-10 WO claimed
US-5218076-A High strength, lightweight fibers and films THE DOW CHEMICAL COMPANY (US) 1993-06-08 US claimed
US-5210171-A Process to polymerize AB-PBO monomer phosphate salts THE DOW CHEMICAL COMPANY (US) 1993-05-11 US claimed
US-5142021-A In dehydrating acid solution containing polyphosphoric acid and methanesulfonic acid THE DOW CHEMICAL COMPANY (US) 1992-08-25 US claimed
US-5068384-A Phosphate salts of AB-polybenzoxazole monomer THE DOW CHEMICAL COMPANY (US) 1991-11-26 US claimed
US-4871570-A DIETETICS; BEVERAGES, DESSERTS GENERAL FOODS CORP. (US) 1989-10-03 US claimed