Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.61 |
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | GAA | P10253 | 5/20 | 0.61 |
| ▸ | CA12 | O43570 | 4/20 | 0.61 |
| ▸ | CA1 | P00915 | 4/20 | 0.61 |
| ▸ | CA2 | P00918 | 4/20 | 0.61 |
| ▸ | CA6 | P23280 | 4/20 | 0.61 |
| ▸ | CA9 | Q16790 | 4/20 | 0.61 |
| ▸ | CA4 | P22748 | 3/20 | 0.61 |
| ▸ | CA7 | P43166 | 3/20 | 0.61 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | CDC25B | P30305 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL180385 | 0.98 | KDM4E (0.64) | KDM4EMAPTGAACA12CA1 | |
| Hydrochloric Acid SCHEMBL9797575 | 0.96 | MAPT (0.61) | KDM4EMAPTGAACA12CA1 | |
| Phosphoric Acid SCHEMBL9468960 | 0.90 | KDM4E (0.55) | KDM4EMAPTGAACA12CA1 | |
| Aniline SCHEMBL7897579 | 0.88 | KDM4E (0.53) | KDM4EMAPTGAACA12CA1 | |
| SCHEMBL10434120 | 0.87 | MAPT (0.52) | KDM4EMAPTGAACA12CA1 | |
| SCHEMBL9328747 | 0.86 | SRD5A2 (0.58) | KDM4EMAPTGAACA12CA1 | |
| SCHEMBL9307729 | 0.83 | KDM4E (0.61) | KDM4EMAPTGAACA12CA1 | |
| SCHEMBL2808434 | 0.82 | CDC25B (0.59) | KDM4EMAPTGAACA12CA1 | |
| SCHEMBL766129 | 0.82 | HSD17B10 (0.52) | KDM4EMAPTGAACA12CA1 | |
| SCHEMBL29412590 | 0.82 | HSD17B10 (0.52) | KDM4EMAPTGAACA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5324808-A | Polybenzimidazoles, polybenzoazoles or polybenzothiazoles | THE DOW CHEMICAL COMPANY (US) | 1994-06-28 | — | — | US | disclosed |
| US-5235023-A | Forming polybenzimidazoles, polybenzthiazoles and polybenz-oxazoles; disodium or dilithium terephthalate monomer | THE DOW CHEMICAL COMPANY (US) | 1993-08-10 | — | — | US | disclosed |
| EP-0449811-A1 | IMPROVED PROCESS FOR SYNTHESIS OF HETEROCYCLIC POLYMERS | THE DOW CHEMICAL COMPANY (US) | 1991-10-09 | — | — | EP | disclosed |
| WO-1990006960-A1 | IMPROVED PROCESS FOR SYNTHESIS OF HETEROCYCLIC POLYMERS | THE DOW CHEMICAL COMPANY (US) | 1990-06-28 | — | — | WO | disclosed |