Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.52 |
| ▸ | AURKA | O14965 | 1/20 | 0.49 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.46 |
| ▸ | COMT | P21964 | 1/20 | 0.44 |
| ▸ | LDHA | P00338 | 1/20 | 0.44 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.42 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.42 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.42 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.42 |
| ▸ | MPL | P40238 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SUMO2 | P61956 | 2/20 | 0.39 |
| ▸ | SUMO1 | P63165 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL703189 | 0.89 | TTR (0.61) | TTRAURKAAURKBCYP1A2CTRB1 | |
| SCHEMBL29409575 | 0.89 | TTR (0.61) | TTRAURKAAURKBCYP1A2CTRB1 | |
| SCHEMBL1805962 | 0.87 | TTR (0.62) | TTRAURKAAURKBCYP1A2CTRB1 | |
| SCHEMBL7710380 | 0.86 | TTR (0.59) | TTRAURKAAURKBCYP1A2CTRB1 | |
| Hydrochloric Acid SCHEMBL11157253 | 0.86 | TTR (0.59) | TTRAURKAAURKBCYP1A2CTRB1 | |
| SCHEMBL6242 | 0.79 | TTR (0.75) | TTRAURKAAURKBCYP1A2CTRB1 | |
| SCHEMBL30233642 | 0.79 | TTR (0.75) | TTRAURKAAURKBCYP1A2CTRB1 | |
| SCHEMBL29363198 | 0.79 | TTR (0.75) | TTRAURKAAURKBCYP1A2CTRB1 | |
| SCHEMBL1805454 | 0.78 | LDHA (0.64) | AURKAAURKBLDHAHSD17B10 | |
| SCHEMBL29564390 | 0.78 | LDHA (0.70) | TTRAURKAAURKBCYP1A2CTRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8404036-B2 | Water-soluble near-infrared absorbing coloring matters and aqueous inks containing same | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2013-03-26 | — | — | US | disclosed |
| US-20110123784-A1 | WATER-SOLUBLE NEAR-INFRARED ABSORBING COLORING MATTERS AND AQUEOUS INKS CONTAINING SAME | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2011-05-26 | — | — | US | disclosed |
| EP-0045278-B1 | REACTIVE DYESTUFFS, THEIR PREPARATION AND THEIR USE | CIBA-GEIGY AG (CH) | 1984-09-19 | — | — | EP | disclosed |
| US-4330469-A | Reactive dyes, processes for their manufacture and their use | CIBA-GEIGY CORPORATION (US) | 1982-05-18 | — | — | US | disclosed |
| EP-0045278-A2 | Reactive dyestuffs, their preparation and their use | CIBA-GEIGY AG (CH) | 1982-02-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110123784-A1 | WATER-SOLUBLE NEAR-INFRARED ABSORBING COLORING MATTERS AND AQUEOUS INKS CONTAINING SAME | IK, RB1, COL1A1 | TTR 594/4885AURKA 2276/4885AURKB 3467/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.