Isovanillic Acid

Isovanillic Acid

SCHEMBL180473

COc1ccc(C(=O)O)cc1O

nearest known ligand 0.72

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.72
CA12 O43570 3/20 0.71
CA1 P00915 3/20 0.71
CA2 P00918 3/20 0.71
CA4 P22748 3/20 0.71
CA6 P23280 3/20 0.71
CA7 P43166 3/20 0.71
CA9 Q16790 3/20 0.71
CA14 Q9ULX7 3/20 0.71
TPMT P51580 2/20 0.71
LMNA P02545 2/20 0.65
MAPK1 P28482 1/20 0.65
RAB9A P51151 1/20 0.65
PTGS2 P35354 2/20 0.63
PKM P14618 2/20 0.62
TUBB4A P04350 1/20 0.62
TUBB P07437 1/20 0.62
TUBA3C P0DPH7 1/20 0.62
TUBA1B P68363 1/20 0.62
TUBA4A P68366 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isovanillic Acid SCHEMBL29883459 1.00 HTT (0.72) HTTCA12CA1CA2CA4
Isovanillic Acid SCHEMBL4450461 0.98 HTT (0.70) HTTCA12CA1CA2CA4
SCHEMBL27575811 0.86 TUBB4A (0.80) HTTLMNARAB9ATUBB4ATUBB
SCHEMBL7820973 0.85 MEN1 (0.59) HTTCA12CA1CA2CA4
Water SCHEMBL28758018 0.84 TUBB4A (0.77) HTTLMNARAB9ATUBB4ATUBB
SCHEMBL29757916 0.84 TUBB1 (0.62) HTTLMNARAB9ATUBB4ATUBB
Vanillic Acid SCHEMBL9711598 0.84 HTT (1.00) HTTCA12CA1CA2CA4
Vanillic Acid SCHEMBL26179 0.84 HTT (1.00) HTTCA12CA1CA2CA4
Vanillic Acid SCHEMBL29378740 0.84 HTT (1.00) HTTCA12CA1CA2CA4
SCHEMBL660390 0.84 TUBB1 (0.62) HTTLMNARAB9ATUBB4ATUBB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2010 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122011393-A Vinyl silicone oil and preparation method thereof 江西科睿新材料有限公司 2026-05-12 CN claimed
US-20260002924-A1 METHOD FOR SELECTING ESTER FUNCTIONAL GROUP-CONTAINING POLYMERS FROM MIXTURE OF ESTER FUNCTIONAL GROUP-CONTAINING POLYMERS AND OTHER TYPES OF POLYMERS KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2026-01-01 US claimed
EP-4655410-A2 O-METHYLATION OF PHENOLIC SUBSTANCES VIA FUNGAL O-METHYLTRANSFERASE Symrise AG (DE) 2025-12-03 EP claimed
EP-4615506-A1 USE OF GSK-3 ACTIVATIOR TO MODULATE PROTEASOME ACTIVITY TO PREVENT AGEING ASSOCIATED CONDITIONS AND DISEASES Sahin, Fikret (TR) 2025-09-17 EP claimed
CN-119874527-A Depsipeptide derivative, preparation method and application thereof 常州工业职业技术学院 2025-04-25 CN claimed
CN-119751188-A Screening preparation method and application of anti-inflammatory and antioxidant activity of ramulus et folium Broussonetiae extract 云南农业大学 2025-04-04 CN claimed
CN-116350654-B Preparation for jellyfish stings and preparation method thereof 中国科学院海洋研究所 2025-03-21 CN claimed
CN-119286137-A Method for preparing novel bumper material by using waste polyolefin plastics 湖南众科新材料有限公司 2025-01-10 CN claimed
WO-2024258363-A1 USE OF GSK-3 ACTIVATIOR TO MODULATE PROTEASOME ACTIVITY TO PREVENT AGEING ASSOCIATED CONDITIONS AND DISEASES SAHIN FIKRET (TR) 2024-12-19 WO claimed
EP-4477693-A1 METHOD FOR SELECTING ESTER FUNCTIONAL GROUP-CONTAINING POLYMERS FROM MIXTURE OF ESTER FUNCTIONAL GROUP-CONTAINING POLYMERS AND OTHER TYPES OF POLYMERS Korea Research Institute of Chemical Technology (KR) 2024-12-18 EP claimed
US-5631038-A COMPOUNDS (TASTANDS) TO REDUCE OR ELIMINATE A BITTER OR METALLIC TASTE ARE ADDED TO FOODS CONTAINING SODIUM CHLORIDE BIORESEARCH, INC. (US) 1997-05-20 US claimed
US-5589277-A INK JET PRINTING, AQUEOUS INKS, FAST DRYING XEROX CORPORATION (US) 1996-12-31 US claimed
EP-0661932-A4 SPECIFIC EATABLE TASTE MODIFIERS. BIORESEARCH INC (US) 1996-06-05 EP claimed
EP-0539274-B1 Method for the synthesis of aldehydes and of their derivatives RHONE POULENC CHIMIE (FR) 1996-04-10 EP claimed
EP-0667246-A1 Recording sheets containing amino acids, hydroxy acids, and polycarboxyl compounds XEROX CORPORATION (US) 1995-08-16 EP claimed
EP-0661932-A1 SPECIFIC EATABLE TASTE MODIFIERS BIORESEARCH, INC. (US) 1995-07-12 EP claimed
WO-1993010677-A1 SPECIFIC EATABLE TASTE MODIFIERS BIORESEARCH, INC. (US) 1993-06-10 WO claimed
EP-0393901-A1 Ink composition ADGER KOGYO CO., LTD. (JP) 1990-10-24 EP claimed
US-4871570-A DIETETICS; BEVERAGES, DESSERTS GENERAL FOODS CORP. (US) 1989-10-03 US claimed
US-4362510-A ESTER OF VANILLIC ACID, METAL OXIDE OR HYDROXIDE THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1982-12-07 US claimed