Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.58 |
| ▸ | TUBB | P07437 | 2/20 | 0.58 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.58 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.58 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.58 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.58 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.58 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.58 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.58 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.58 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.58 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.58 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.58 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.58 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL760262 | 0.85 | MEN1 (0.82) | MEN1RAB9AKMT2AHTTGAA | |
| SCHEMBL30921173 | 0.85 | MEN1 (0.82) | MEN1RAB9AKMT2AHTTGAA | |
| SCHEMBL3230564 | 0.85 | MEN1 (0.59) | MEN1RAB9AKMT2ATUBB4ATUBB | |
| SCHEMBL339242 | 0.85 | CA12 (0.71) | MEN1RAB9AKMT2AHTTGAA | |
| Isovanillic Acid SCHEMBL180473 | 0.85 | HTT (0.72) | RAB9ATUBB4ATUBBTUBA3CTUBA1B | |
| Isovanillic Acid SCHEMBL29883459 | 0.85 | HTT (0.72) | RAB9ATUBB4ATUBBTUBA3CTUBA1B | |
| Isovanillic Acid SCHEMBL4450461 | 0.83 | HTT (0.70) | RAB9ATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL27468173 | 0.83 | CA12 (0.69) | MEN1RAB9AKMT2AGAACA12 | |
| SCHEMBL27575811 | 0.82 | TUBB4A (0.80) | MEN1RAB9AKMT2ATUBB4ATUBB | |
| SCHEMBL28568628 | 0.82 | TUBB4A (0.55) | MEN1RAB9AKMT2ATUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210188914-A1 | HYBRID CYCLIC LIBRARIES AND SCREENS THEREOF | THE JOHNS HOPKINS UNIVERSITY | 2021-06-24 | — | — | US | disclosed |
| US-10954273-B2 | Hybrid cyclic libraries and screens thereof | THE JOHNS HOPKINS UNIVERSITY (US) | 2021-03-23 | — | — | US | disclosed |
| US-20190389911-A1 | HYBRID CYCLIC LIBRARIES AND SCREENS THEREOF | THE JOHNS HOPKINS UNIVERSITY | 2019-12-26 | — | — | US | disclosed |
| US-10414801-B2 | Hybrid cyclic libraries and screens thereof | THE JOHNS HOPKINS UNIVERSITY (US) | 2019-09-17 | — | — | US | disclosed |
| US-20180222942-A1 | HYBRID CYCLIC LIBRARIES AND SCREENS THEREOF | THE JOHNS HOPKINS UNIVERSITY | 2018-08-09 | — | — | US | disclosed |
| US-20180222942-A1 | HYBRID CYCLIC LIBRARIES AND SCREENS THEREOF | THE JOHNS HOPKINS UNIVERSITY | 2018-08-09 | — | — | US | disclosed |
| US-9783577-B2 | Hybrid cyclic libraries and screens thereof | THE JOHNS HOPKINS UNIVERSITY (US) | 2017-10-10 | — | — | US | disclosed |
| US-9783577-B2 | Hybrid cyclic libraries and screens thereof | THE JOHNS HOPKINS UNIVERSITY (US) | 2017-10-10 | — | — | US | disclosed |
| US-20160115203-A1 | HYBRID CYCLIC LIBRARIES AND SCREENS THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-04-28 | — | — | US | disclosed |
| US-20160115203-A1 | HYBRID CYCLIC LIBRARIES AND SCREENS THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-04-28 | — | — | US | disclosed |
| US-9250237-B2 | Hybrid cyclic libraries and screens thereof | THE JOHNS HOPKINS UNIVERSITY (US) | 2016-02-02 | — | — | US | disclosed |
| US-9250237-B2 | Hybrid cyclic libraries and screens thereof | THE JOHNS HOPKINS UNIVERSITY (US) | 2016-02-02 | — | — | US | disclosed |
| US-20140073581-A1 | Hybrid Cyclic Libraries and Screens Thereof | THE JOHNS HOPKINS UNIVERSITY | 2014-03-13 | — | — | US | disclosed |
| US-20140073581-A1 | Hybrid Cyclic Libraries and Screens Thereof | THE JOHNS HOPKINS UNIVERSITY | 2014-03-13 | — | — | US | disclosed |
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140073581-A1 | Hybrid Cyclic Libraries and Screens Thereof | CACYBP, HSPBP1, PEBP1 | MEN1 2998/4885RAB9A 2030/4885KMT2A 4734/4885 |
| US-10414801-B2 | Hybrid cyclic libraries and screens thereof | CACYBP, HSPBP1, PEBP1 | MEN1 2998/4885RAB9A 2030/4885KMT2A 4734/4885 |
| US-10954273-B2 | Hybrid cyclic libraries and screens thereof | CACYBP, HSPBP1, PEBP1 | MEN1 2998/4885RAB9A 2030/4885KMT2A 4734/4885 |
| US-20190389911-A1 | HYBRID CYCLIC LIBRARIES AND SCREENS THEREOF | CACYBP, HSPBP1, PEBP1 | MEN1 2998/4885RAB9A 2030/4885KMT2A 4734/4885 |
| US-20210188914-A1 | HYBRID CYCLIC LIBRARIES AND SCREENS THEREOF | CACYBP, HSPBP1, PEBP1 | MEN1 2998/4885RAB9A 2030/4885KMT2A 4734/4885 |
| US-20180222942-A1 | HYBRID CYCLIC LIBRARIES AND SCREENS THEREOF | CACYBP, HSPBP1, PEBP1 | MEN1 2998/4885RAB9A 2030/4885KMT2A 4734/4885 |
| US-20160115203-A1 | HYBRID CYCLIC LIBRARIES AND SCREENS THEREOF | CACYBP, HSPBP1, PEBP1 | MEN1 2998/4885RAB9A 2030/4885KMT2A 4734/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.