SCHEMBL660390

SCHEMBL660390

COc1ccc(C(C)=O)cc1O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TUBB1 Q9H4B7 3/20 0.62
TUBB4A P04350 2/20 0.62
TUBB P07437 2/20 0.62
TUBA3C P0DPH7 2/20 0.62
TUBA1B P68363 2/20 0.62
TUBA4A P68366 2/20 0.62
TUBB4B P68371 2/20 0.62
TUBB3 Q13509 2/20 0.62
TUBB2A Q13885 2/20 0.62
TUBB8 Q3ZCM7 2/20 0.62
TUBA3E Q6PEY2 2/20 0.62
TUBA1A Q71U36 2/20 0.62
TUBA1C Q9BQE3 2/20 0.62
TUBB6 Q9BUF5 2/20 0.62
TUBB2B Q9BVA1 2/20 0.62
LMNA P02545 1/20 0.57
RECQL P46063 1/20 0.56
ALDH1A1 P00352 3/20 0.56
MEN1 O00255 2/20 0.56
KMT2A Q03164 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29757916 1.00 TUBB1 (0.62) TUBB1TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL27575811 0.86 TUBB4A (0.80) TUBB1TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL3230564 0.85 MEN1 (0.59) TUBB1TUBB4ATUBBTUBA3CTUBA1B
Apocynin SCHEMBL464770 0.84 MEN1 (0.75) LMNAALDH1A1MEN1KMT2ASLC22A6
Isovanillic Acid SCHEMBL29883459 0.84 HTT (0.72) TUBB1TUBB4ATUBBTUBA3CTUBA1B
Apocynin SCHEMBL109514 0.84 MEN1 (0.75) LMNAALDH1A1MEN1KMT2ASLC22A6
Apocynin SCHEMBL29364797 0.84 MEN1 (0.75) LMNAALDH1A1MEN1KMT2ASLC22A6
Water SCHEMBL28758018 0.84 TUBB4A (0.77) TUBB1TUBB4ATUBBTUBA3CTUBA1B
Isovanillic Acid SCHEMBL180473 0.84 HTT (0.72) TUBB1TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL29399077 0.83 TSHR (0.73) LMNAALDH1A1MEN1KMT2ACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 300 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115541746-B Construction method and identification method of fingerprint of different-base radix cynanchi atrati and Laogui 广东一方制药有限公司 2023-12-12 CN claimed
CN-115541746-A Method for constructing and identifying fingerprint spectrums of different basic sources cynanchum atratum and old melon head 广东一方制药有限公司 2022-12-30 CN claimed
CN-110963906-B Anti-tumor compound aiming at Fyn-CD147 signal channel target spot and preparation method and application thereof 中南大学湘雅医院 2022-07-22 CN claimed
CN-110963906-A Anti-tumor compound aiming at Fyn-CD147 signal channel target spot and preparation method and application thereof 中南大学湘雅医院 2020-04-07 CN claimed
CN-105623439-A Anti-aging emulsion paint for exterior wall SHENYANG SHUNFENG XINCHENG BUILDING MAT CO LTD 2016-06-01 CN claimed
US-20080255228-A1 Ascorbic Acid Complexes for Skin Care Including Treatment of Dark Skin & Wrinkles BIODERM RESEARCH (US) 2008-10-16 US claimed
US-20080254130-A1 Skin Antiaging & Brightening via Multi-function Treatment of Enzyme Dysfunction BIODERM RESEARCH (US) 2008-10-16 US claimed
US-7427690-B2 Multifunction “crown complexes” from amino acids and peptides for skin and hair restoration BIODERM RESEARCH (US) 2008-09-23 US claimed
US-12565518-B2 Hybrid cyclic libraries and screens thereof THE JOHNS HOPKINS UNIVERSITY (US) 2026-03-03 US disclosed
EP-4626412-A1 FORMULATION COMPRISING APOCYNIN AND PAEONOL AKL Research&Development Ltd (GB) 2025-10-08 EP disclosed
CN-120053509-A Radix cynanchi atrati extract and preparation method and application thereof 淮北师范大学 2025-05-30 CN disclosed
CN-116102426-B Wide-absorption polymerizable ketene photoinitiator and preparation method and application thereof 合肥工业大学 2025-04-29 CN disclosed
EP-4510992-A2 SKIN BARRIER PROTECTIVE DELIVERY SYSTEMS AND METHODS THEREOF Bobo Labs Inc. (US) 2025-02-26 EP disclosed
CN-119343126-A Skin barrier protection delivery system and method thereof 宝宝实验室公司 2025-01-21 CN disclosed
EP-0372900-A2 Process for drying hydrogen fluoride - carboxylic acid mixtures HOECHST CELANESE CORPORATION (US) 1990-06-13 EP disclosed
US-4920133-A Quinoline derivatives and use thereof as antagonists of leukotriene D4 RORER PHARMACEUTICAL CORP. (US) 1990-04-24 US disclosed
US-4894482-A SOLVENT EXTRACTION, DISTILLATION HOECHST CELANESE CORPORATION (US) 1990-01-16 US disclosed
WO-1989004303-A1 QUINOLINE DERIVATIVES AS ANTAGONISTS OF LEUKOTRIENE D4 RORER INTERNATIONAL (OVERSEAS) INC. (US) 1989-05-18 WO disclosed
US-4096112-A POLYVINYL CHLORIDE LABAZ (FR) 1978-06-20 US disclosed
US-4024155-A 2-(3'-Methoxy-4'-hydroxy-phenol)-indole LABAZ (FR) 1977-05-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12565518-B2 Hybrid cyclic libraries and screens thereof NOLC1, BCL6, CHP1 TUBB1 2390/4885TUBB4A 3163/4885TUBB 2983/4885
US-20080254130-A1 Skin Antiaging & Brightening via Multi-function Treatment of Enzyme Dysfunction PSMB1, PLOD3, CUTA TUBB1 1248/4885TUBB4A 1677/4885TUBB 1349/4885
US-20080255228-A1 Ascorbic Acid Complexes for Skin Care Including Treatment of Dark Skin & Wrinkles PROC, COL1A1, CUTA TUBB1 1292/4885TUBB4A 2663/4885TUBB 1436/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.