Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.48 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.48 |
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | ALPI | P09923 | 1/20 | 0.38 |
| ▸ | XIAP | P98170 | 1/20 | 0.38 |
| ▸ | GRIA2 | P42262 | 4/20 | 0.36 |
| ▸ | GRIA1 | P42261 | 3/20 | 0.36 |
| ▸ | GRIA3 | P42263 | 3/20 | 0.36 |
| ▸ | GRIA4 | P48058 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 2/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Histidine SCHEMBL851432 | 1.00 | PTGS1 (0.48) | PTGS1SLC7A11SLC7A5CYP3A4CYP1A2 | |
| Histidine SCHEMBL22091426 | 1.00 | PTGS1 (0.48) | PTGS1SLC7A11SLC7A5CYP3A4CYP1A2 | |
| Histidine SCHEMBL27769589 | 1.00 | PTGS1 (0.48) | PTGS1SLC7A11SLC7A5CYP3A4CYP1A2 | |
| Histidine SCHEMBL4452747 | 1.00 | PTGS1 (0.48) | PTGS1SLC7A11SLC7A5CYP3A4CYP1A2 | |
| Histidine SCHEMBL1673287 | 1.00 | PTGS1 (0.48) | PTGS1SLC7A11SLC7A5CYP3A4CYP1A2 | |
| Histidine SCHEMBL28655326 | 0.98 | PTGS1 (0.47) | PTGS1SLC7A11SLC7A5CYP3A4CYP1A2 | |
| Histidine SCHEMBL28511880 | 0.98 | PTGS1 (0.47) | PTGS1SLC7A11SLC7A5CYP3A4CYP1A2 | |
| Histidine SCHEMBL28203991 | 0.98 | PTGS1 (0.47) | PTGS1SLC7A11SLC7A5CYP3A4CYP1A2 | |
| Histidine SCHEMBL1692193 | 0.98 | PTGS1 (0.47) | PTGS1SLC7A11SLC7A5CYP3A4CYP1A2 | |
| Histidine SCHEMBL1257407 | 0.94 | PTGS1 (0.43) | PTGS1SLC7A11SLC7A5CYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10053491-B2 | Method for producing peptide hydrazide, peptide amide, and peptide thioester | AJINOMOTO CO., INC. (JP) | 2018-08-21 | — | — | US | disclosed |
| US-20160264626-A1 | METHOD FOR PRODUCING PEPTIDE HYDRAZIDE, PEPTIDE AMIDE, AND PEPTIDE THIOESTER | AJINOMOTO CO., INC. (JP) | 2016-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160264626-A1 | METHOD FOR PRODUCING PEPTIDE HYDRAZIDE, PEPTIDE AMIDE, AND PEPTIDE THIOESTER | VIP, PPT1, NPPA | PTGS1 4501/4885SLC7A11 1331/4885SLC7A5 2533/4885 |
| US-10053491-B2 | Method for producing peptide hydrazide, peptide amide, and peptide thioester | VIP, PPT1, NPPA | PTGS1 4501/4885SLC7A11 1331/4885SLC7A5 2533/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.