Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 6/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | GRM5 | P41594 | 1/20 | 0.49 |
| ▸ | VNN1 | O95497 | 1/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | F10 | P00742 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18048981 | 0.87 | KDR (0.56) | L3MBTL1RAB9ASMN1; SMN2KMT2AVNN1 | |
| SCHEMBL18048969 | 0.86 | VNN1 (0.51) | L3MBTL1KMT2AVNN1ALDH1A1MAPT | |
| SCHEMBL18049006 | 0.85 | KDR (0.62) | L3MBTL1RAB9ASMN1; SMN2KMT2ALMNA | |
| SCHEMBL18049798 | 0.81 | VNN1 (0.46) | RAB9ASMN1; SMN2KMT2AVNN1NPC1 | |
| SCHEMBL28764679 | 0.78 | L3MBTL1 (0.66) | L3MBTL1RAB9ASMN1; SMN2KMT2ABRD4 | |
| SCHEMBL29837506 | 0.78 | L3MBTL1 (0.66) | L3MBTL1RAB9ASMN1; SMN2KMT2ABRD4 | |
| SCHEMBL18048975 | 0.77 | NAMPT (0.47) | RAB9ASMN1; SMN2NPC1ALDH1A1MAPT | |
| SCHEMBL18070912 | 0.77 | KDM4E (0.47) | L3MBTL1KMT2AVNN1ALDH1A1MAPT | |
| SCHEMBL18048992 | 0.76 | CNR2 (0.41) | VNN1ALDH1A1TDP1MAPT | |
| SCHEMBL15528783 | 0.75 | KMT2A (0.56) | L3MBTL1KMT2AVNN1ALDH1A1F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016144792-A1 | ALPHA 7 NICOTINIC ACETYLCHOLINE RECEPTOR ALLOSTERIC MODULATORS, THEIR DERIVATIVES AND USES THEREOF | ALPHARMAGEN, LLC (US) | 2016-09-15 | — | — | WO | disclosed |
| WO-2016144792-A1 | ALPHA 7 NICOTINIC ACETYLCHOLINE RECEPTOR ALLOSTERIC MODULATORS, THEIR DERIVATIVES AND USES THEREOF | ALPHARMAGEN, LLC (US) | 2016-09-15 | — | — | WO | disclosed |
| WO-2016144797-A1 | ALPHA 7 NICOTINIC ACETYLCHOLINE RECEPTOR ALLOSTERIC MODULATORS, THEIR DERIVATIVES AND USES THEREOF | ALPHARMAGEN, LLC (US) | 2016-09-15 | — | — | WO | disclosed |
| WO-2016144797-A1 | ALPHA 7 NICOTINIC ACETYLCHOLINE RECEPTOR ALLOSTERIC MODULATORS, THEIR DERIVATIVES AND USES THEREOF | ALPHARMAGEN, LLC (US) | 2016-09-15 | — | — | WO | disclosed |