Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.52 |
| ▸ | VNN1 | O95497 | 1/20 | 0.52 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | PPIA | P62937 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.44 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.44 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18070983 | 1.00 | EGLN1 (0.52) | EGLN1VNN1GRM4HTTKMT2A | |
| SCHEMBL18048951 | 0.89 | EGLN1 (0.50) | EGLN1VNN1HTTKMT2AKDR | |
| SCHEMBL18070981 | 0.89 | EGLN1 (0.50) | EGLN1VNN1HTTKMT2AKDR | |
| SCHEMBL18070985 | 0.87 | VNN1 (0.53) | EGLN1VNN1GRM4HTTKMT2A | |
| SCHEMBL18049027 | 0.87 | VNN1 (0.53) | EGLN1VNN1GRM4HTTKMT2A | |
| SCHEMBL18070979 | 0.86 | KDR (0.53) | VNN1HTTKMT2AKDRMEN1 | |
| SCHEMBL18048947 | 0.86 | KDR (0.53) | VNN1HTTKMT2AKDRMEN1 | |
| SCHEMBL18070944 | 0.85 | EGLN1 (0.51) | EGLN1GRM4HTTKMT2ATP53 | |
| SCHEMBL18070931 | 0.85 | EGLN1 (0.51) | EGLN1GRM4HTTKMT2ATP53 | |
| SCHEMBL18070982 | 0.85 | EGLN1 (0.51) | EGLN1GRM4HTTKMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016144797-A1 | ALPHA 7 NICOTINIC ACETYLCHOLINE RECEPTOR ALLOSTERIC MODULATORS, THEIR DERIVATIVES AND USES THEREOF | ALPHARMAGEN, LLC (US) | 2016-09-15 | — | — | WO | claimed |
| WO-2016144797-A1 | ALPHA 7 NICOTINIC ACETYLCHOLINE RECEPTOR ALLOSTERIC MODULATORS, THEIR DERIVATIVES AND USES THEREOF | ALPHARMAGEN, LLC (US) | 2016-09-15 | — | — | WO | disclosed |