Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.45 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18050329 | 1.00 | SMN1; SMN2 (0.58) | SMN1; SMN2PKMKMT2AALDH1A1HSD17B10 | |
| SCHEMBL7746320 | 0.87 | SMN1; SMN2 (0.59) | SMN1; SMN2PKMKMT2AALDH1A1HSD17B10 | |
| SCHEMBL18050343 | 0.85 | NPC1 (0.61) | KMT2AALDH1A1HSD17B10CES2CES1 | |
| SCHEMBL19875762 | 0.85 | NPC1 (0.61) | SMN1; SMN2PKMKMT2AALDH1A1TSHR | |
| SCHEMBL19875763 | 0.85 | NPC1 (0.61) | SMN1; SMN2PKMKMT2AALDH1A1TSHR | |
| SCHEMBL18050341 | 0.85 | NPC1 (0.61) | KMT2AALDH1A1HSD17B10CES2CES1 | |
| SCHEMBL896787 | 0.82 | CES2 (0.62) | SMN1; SMN2PKMKMT2AALDH1A1HSD17B10 | |
| SCHEMBL9364011 | 0.81 | SMN1; SMN2 (0.54) | SMN1; SMN2PKMKMT2AALDH1A1HSD17B10 | |
| SCHEMBL19875689 | 0.81 | KMT2A (0.57) | SMN1; SMN2PKMKMT2AALDH1A1MEN1 | |
| SCHEMBL19875690 | 0.81 | KMT2A (0.57) | SMN1; SMN2PKMKMT2AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3268398-B1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA SRL (IT) | 2019-05-15 | — | — | EP | disclosed |
| US-10246532-B2 | Catalyst components for the polymerization of olefins | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2019-04-02 | — | — | US | disclosed |
| US-20180051106-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2018-02-22 | — | — | US | disclosed |
| EP-3268398-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | Basell Poliolefine Italia S.r.l. (IT) | 2018-01-17 | — | — | EP | disclosed |
| WO-2016142377-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2016-09-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180051106-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | C1S, CCNT1, COG1 | SMN1; SMN2 3916/4885PKM 1684/4885KMT2A 1960/4885 |
| US-10246532-B2 | Catalyst components for the polymerization of olefins | C1S, CCNT1, COG1 | SMN1; SMN2 3916/4885PKM 1684/4885KMT2A 1960/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.