SCHEMBL1805168

SCHEMBL1805168

O=S(=O)(O)c1ccc2ccccc2c1S

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTRB1 P17538 1/20 0.50
MPL P40238 4/20 0.45
CTRC Q99895 2/20 0.45
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA9 Q16790 1/20 0.41
ALDH1A1 P00352 4/20 0.41
HSD17B10 Q99714 3/20 0.41
CYP2A6 P11509 1/20 0.41
TSHR P16473 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
HIF1A Q16665 2/20 0.40
CYP1B1 Q16678 1/20 0.40
CYP2D6 P10635 1/20 0.39
TTR P02766 1/20 0.39
ERN1 O75460 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2C9 P11712 1/20 0.39
ALOX15 P16050 1/20 0.39
ATIC P31939 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1806305 0.81 CA1 (0.60) CA1CA2CA9ALDH1A1HSD17B10
SCHEMBL41541 0.80 CYP2D6 (0.53) CTRB1MPLCTRCCA1CA2
SCHEMBL2785876 0.80 CTRB1 (0.53) CTRB1MPLCTRCCA1CA2
SCHEMBL29972292 0.80 CTRB1 (0.53) CTRB1MPLCTRCCA1CA2
SCHEMBL8645212 0.78 CTRB1 (0.51) CTRB1MPLCTRCCA1CA2
SCHEMBL88069 0.78 CTRB1 (0.64) CTRB1MPLCTRCHIF1ACYP2D6
SCHEMBL8835967 0.78 CYP2D6 (0.51) CTRB1MPLCTRCCA1CA2
SCHEMBL3233245 0.78 CYP2D6 (0.51) CTRB1MPLCTRCCA1CA2
SCHEMBL5077155 0.78 CYP2D6 (0.51) CTRB1MPLCTRCCA1CA2
Water SCHEMBL669870 0.78 CYP2D6 (0.51) CTRB1MPLCTRCCA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404036-B2 Water-soluble near-infrared absorbing coloring matters and aqueous inks containing same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2013-03-26 US disclosed
US-20110123784-A1 WATER-SOLUBLE NEAR-INFRARED ABSORBING COLORING MATTERS AND AQUEOUS INKS CONTAINING SAME NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2011-05-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110123784-A1 WATER-SOLUBLE NEAR-INFRARED ABSORBING COLORING MATTERS AND AQUEOUS INKS CONTAINING SAME IK, RB1, COL1A1 CTRB1 2445/4885MPL 4659/4885CTRC 2073/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.