SCHEMBL18057702

SCHEMBL18057702

c1ccc(-n2c3ccccc3c3c4nccnc4c4c5ccccc5n(-c5ccccc5)c4c32)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.52
KDM4E B2RXH2 1/20 0.52
ATM Q13315 1/20 0.52
PDE4A P27815 4/20 0.37
PDE4B Q07343 3/20 0.37
PDE4C Q08493 3/20 0.37
PDE4D Q08499 3/20 0.37
GABRP O00591 1/20 0.37
GABRD O14764 1/20 0.37
GABRA1 P14867 1/20 0.37
GABRB1 P18505 1/20 0.37
GABRG2 P18507 1/20 0.37
GABRB3 P28472 1/20 0.37
GABRA5 P31644 1/20 0.37
GABRA3 P34903 1/20 0.37
GABRA2 P47869 1/20 0.37
GABRB2 P47870 1/20 0.37
GABRA4 P48169 1/20 0.37
GABRE P78334 1/20 0.37
GABRA6 Q16445 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18057713 0.94 KDM4E (0.46) L3MBTL1KDM4EATMPDE4APDE4B
SCHEMBL18057716 0.92 L3MBTL1 (0.44) L3MBTL1KDM4EATMPDE4APDE4B
SCHEMBL18057706 0.92 KDM4E (0.44) L3MBTL1KDM4EATMPDE4APDE4B
SCHEMBL18057772 0.90 L3MBTL1 (0.42) L3MBTL1KDM4EATMPDE4APDE4B
SCHEMBL18057774 0.90 KDM4E (0.42) L3MBTL1KDM4EATMPDE4APDE4B
SCHEMBL18057704 0.90 KDM4E (0.42) L3MBTL1KDM4EATMPDE4APDE4B
SCHEMBL18057866 0.90 KDM4E (0.42) L3MBTL1KDM4EATMPDE4APDE4B
SCHEMBL18057701 0.89 KDM4E (0.47) L3MBTL1KDM4EATMPDE4APDE4B
SCHEMBL18057769 0.89 L3MBTL1 (0.41) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL18057762 0.87 KCNH2 (0.40) L3MBTL1KDM4EATMMAPK1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10680183-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-06-09 US disclosed
US-20160260909-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2016-09-08 US disclosed
US-20160260909-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2016-09-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10680183-B2 Organic electroluminescent materials and devices PNMT, CYCS, NES L3MBTL1 1086/4885KDM4E 2235/4885ATM 4136/4885
US-20160260909-A1 Organic Electroluminescent Materials and Devices PNMT, CYCS, NES L3MBTL1 1086/4885KDM4E 2235/4885ATM 4136/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.