Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HASPIN | Q8TF76 | 8/20 | 0.40 |
| ▸ | TNF | P01375 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 3/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.32 |
| ▸ | CDK9 | P50750 | 2/20 | 0.32 |
| ▸ | TDO2 | P48775 | 2/20 | 0.31 |
| ▸ | CLK1 | P49759 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.30 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.30 |
| ▸ | IKBKB | O14920 | 2/20 | 0.30 |
| ▸ | CHUK | O15111 | 1/20 | 0.30 |
| ▸ | LCK | P06239 | 1/20 | 0.30 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18058240 | 1.00 | HASPIN (0.40) | HASPINTNFPIM1CCNT1CDK9 | |
| SCHEMBL18057950 | 0.91 | — | — | |
| SCHEMBL18059387 | 0.85 | TDO2 (0.31) | TDO2PIK3CD | |
| SCHEMBL18058239 | 0.85 | TDO2 (0.33) | TDO2PIK3CD | |
| SCHEMBL18058070 | 0.85 | HASPIN (0.36) | HASPINTNFTDO2CLK1IKBKB | |
| SCHEMBL18058072 | 0.85 | HASPIN (0.36) | HASPINTNFTDO2CLK1IKBKB | |
| SCHEMBL18058247 | 0.85 | TNF (0.33) | TNF | |
| SCHEMBL18057978 | 0.85 | TNF (0.41) | TNF | |
| SCHEMBL16940910 | 0.84 | — | — | |
| SCHEMBL18057960 | 0.84 | ABCB1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10680183-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2020-06-09 | — | — | US | disclosed |
| US-20160260909-A1 | Organic Electroluminescent Materials and Devices | UNIVERSAL DISPLAY CORPORATION | 2016-09-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10680183-B2 | Organic electroluminescent materials and devices | PNMT, CYCS, NES | HASPIN 3855/4885TNF 4821/4885PIM1 365/4885 |
| US-20160260909-A1 | Organic Electroluminescent Materials and Devices | PNMT, CYCS, NES | HASPIN 3855/4885TNF 4821/4885PIM1 365/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.