Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FEN1 | P39748 | 19/20 | 0.43 |
| ▸ | ALOX5AP | P20292 | 15/20 | 0.43 |
| ▸ | LPL | P06858 | 1/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20968600 | 0.80 | LIPG (0.49) | LPLLIPG | |
| SCHEMBL31401292 | 0.79 | LPL (0.37) | LPLLIPG | |
| SCHEMBL2659535 | 0.79 | LPL (0.37) | LPLLIPG | |
| SCHEMBL2659046 | 0.78 | CYP17A1 (0.40) | LPLLIPG | |
| SCHEMBL22040321 | 0.76 | PDK2 (0.42) | FEN1ALOX5AP | |
| SCHEMBL24630498 | 0.75 | LPL (0.46) | LPLLIPG | |
| SCHEMBL1494570 | 0.75 | LPL (0.40) | LPLLIPG | |
| SCHEMBL2659000 | 0.74 | KDM4E (0.35) | LPLLIPG | |
| SCHEMBL22040947 | 0.73 | BRD4 (0.35) | LPLLIPG | |
| SCHEMBL15915817 | 0.73 | FEN1 (0.50) | FEN1ALOX5APLPLLIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3070085-A1 | FLAP MODULATORS | Janssen Pharmaceutica N.V. (BE) | 2016-09-21 | — | — | EP | disclosed |