SCHEMBL1806151

SCHEMBL1806151

Cc1cccc(S(=O)(=O)O)c1C[O]

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MYC P01106 1/20 0.41
TTR P02766 2/20 0.39
CYP1A2 P05177 2/20 0.36
RAPGEF4 Q8WZA2 1/20 0.36
SUMO2 P61956 2/20 0.35
SUMO1 P63165 2/20 0.35
SENP7 Q9BQF6 2/20 0.35
SENP2 Q9HC62 2/20 0.35
SENP3 Q9H4L4 1/20 0.35
SENP1 Q9P0U3 1/20 0.35
SNCA P37840 1/20 0.34
KMT2A Q03164 2/20 0.33
ESR2 Q92731 2/20 0.33
MEN1 O00255 1/20 0.33
ESR1 P03372 1/20 0.33
GAA P10253 1/20 0.33
ATIC P31939 1/20 0.33
ALDH1A1 P00352 1/20 0.33
FABP4 P15090 1/20 0.33
CCNA2 P20248 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1806780 0.85 MYC (0.39) MYCTTRCYP1A2RAPGEF4SUMO2
SCHEMBL1806155 0.85 MYC (0.41) MYCTTRCYP1A2RAPGEF4SUMO2
SCHEMBL1275170 0.85 RAPGEF4 (0.42) MYCTTRCYP1A2RAPGEF4SUMO2
SCHEMBL1806021 0.83 MYC (0.40) MYCTTRCYP1A2RAPGEF4SUMO2
SCHEMBL1806026 0.83 CYP1A2 (0.42) MYCTTRCYP1A2RAPGEF4SUMO2
SCHEMBL1806784 0.81 MYC (0.39) MYCTTRCYP1A2RAPGEF4SUMO2
SCHEMBL1807206 0.81 CA2 (0.42) CDK2CA1CA2CA4CA7
SCHEMBL6737495 0.80 MYC (0.38) MYCTTRCYP1A2RAPGEF4KMT2A
SCHEMBL15541482 0.80 MYC (0.38) MYCTTRCYP1A2RAPGEF4SUMO2
SCHEMBL28557476 0.79 MYC (0.37) MYCTTRCYP1A2RAPGEF4SUMO2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404036-B2 Water-soluble near-infrared absorbing coloring matters and aqueous inks containing same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2013-03-26 US disclosed
US-20110123784-A1 WATER-SOLUBLE NEAR-INFRARED ABSORBING COLORING MATTERS AND AQUEOUS INKS CONTAINING SAME NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2011-05-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110123784-A1 WATER-SOLUBLE NEAR-INFRARED ABSORBING COLORING MATTERS AND AQUEOUS INKS CONTAINING SAME IK, RB1, COL1A1 MYC 3750/4885TTR 594/4885CYP1A2 487/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.