Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 4/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 4/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16974408 | 0.84 | KMT2A (0.70) | SLC9A1KMT2AMAPK1CYP2C19MEN1 | |
| SCHEMBL439391 | 0.81 | SLC9A1 (0.64) | SLC9A1KMT2AMAPK1CYP2C19MEN1 | |
| SCHEMBL22494210 | 0.81 | SLC9A1 (0.64) | SLC9A1KMT2AMAPK1CYP2C19MEN1 | |
| SCHEMBL3079415 | 0.81 | SLC9A1 (0.64) | SLC9A1KMT2AMAPK1CYP2C19MEN1 | |
| SCHEMBL29479871 | 0.81 | SLC9A1 (0.64) | SLC9A1KMT2AMAPK1CYP2C19MEN1 | |
| SCHEMBL27922578 | 0.81 | SLC9A1 (0.64) | SLC9A1KMT2AMAPK1CYP2C19MEN1 | |
| SCHEMBL9642423 | 0.79 | SLC9A1 (0.62) | SLC9A1KMT2AMAPK1CYP2C19MEN1 | |
| SCHEMBL10608005 | 0.79 | SLC9A1 (0.62) | SLC9A1KMT2AMAPK1CYP2C19MEN1 | |
| SCHEMBL2491809 | 0.78 | SLC9A1 (1.00) | SLC9A1KMT2AMAPK1CYP2C19MEN1 | |
| SCHEMBL29479875 | 0.78 | SLC9A1 (1.00) | SLC9A1KMT2AMAPK1CYP2C19MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160257709-A1 | HEMIASTERLIN DERIVATIVES FOR CONJUGATION AND THERAPY | SUTRO BIOPHARMA, INC. | 2016-09-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160257709-A1 | HEMIASTERLIN DERIVATIVES FOR CONJUGATION AND THERAPY | CYP17A1, HSD17B7, SHBG | SLC9A1 3408/4885KMT2A 2712/4885MAPK1 3157/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.