Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 5/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5693922 | 0.92 | TDP1 (0.63) | PARP1TDP1MAPTALDH1A1CYP3A4 | |
| SCHEMBL27663754 | 0.85 | TDP1 (0.48) | TDP1MAPTALDH1A1CYP3A4TSHR | |
| SCHEMBL436565 | 0.84 | LMNA (0.56) | TDP1MAPTALDH1A1CYP3A4TSHR | |
| SCHEMBL284729 | 0.83 | TDP1 (0.73) | PARP1TDP1MAPTALDH1A1CYP3A4 | |
| SCHEMBL100752 | 0.83 | CDC25B (0.55) | TDP1MAPTALDH1A1CYP3A4TSHR | |
| SCHEMBL30241864 | 0.83 | CDC25B (0.55) | TDP1MAPTALDH1A1CYP3A4TSHR | |
| SCHEMBL30508415 | 0.83 | PRKCI (0.53) | TDP1MAPTALDH1A1CYP3A4TSHR | |
| SCHEMBL1026788 | 0.83 | PRKCI (0.53) | TDP1MAPTALDH1A1CYP3A4TSHR | |
| SCHEMBL29503140 | 0.82 | PRSS1 (0.61) | PARP1TDP1MAPTALDH1A1LCK | |
| SCHEMBL1002832 | 0.82 | PRSS1 (0.61) | PARP1TDP1MAPTALDH1A1LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 187 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4891408-A | POLYEPOXIDES, PREPREGS | AMOCO CORPORATION (US) | 1990-01-02 | — | — | US | claimed |
| EP-0239804-B1 | EPOXY RESINS BASED ON TETRAGLYCIDYL DIAMINES AND THE USE THEREOF FOR EPOXY SYSTEMS AND PREPREGS | AMOCO CORPORATION (US) | 1989-08-09 | — | — | EP | claimed |
| US-4814414-A | POLYAMINE CURING AGENT, FIBER REINFORCEMENT, CO-POLYEPOXIDES; AIRCRAFT PREPREGS | AMOCO CORPORATION (US) | 1989-03-21 | — | — | US | claimed |
| EP-0239804-A1 | Epoxy resins based on tetraglycidyl diamines and the use thereof for epoxy systems and prepregs | AMOCO CORPORATION (US) | 1987-10-07 | — | — | EP | claimed |
| US-4680341-A | Epoxy resins based on tetraglycidyl diamines | UNION CARBIDE CORPORATION (US) | 1987-07-14 | — | — | US | claimed |
| US-20240277852-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2024-08-22 | — | — | US | disclosed |
| EP-4341254-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Dana-Farber Cancer Institute, Inc. (US) | 2024-03-27 | — | — | EP | disclosed |
| CN-114315834-B | Imidazolone derivatives and their use in medicine | 成都百裕制药股份有限公司 | 2024-01-05 | — | — | CN | disclosed |
| US-20230165867-A1 | IMIDAZOLIDINONE DERIVATIVES AND MEDICAL USE THEREOF | KANGBAIDA (SICHUAN) BIOTECHNOLOGY CO., LTD. (CN) | 2023-06-01 | — | — | US | disclosed |
| US-20230165867-A1 | IMIDAZOLIDINONE DERIVATIVES AND MEDICAL USE THEREOF | KANGBAIDA (SICHUAN) BIOTECHNOLOGY CO., LTD. (CN) | 2023-06-01 | — | — | US | disclosed |
| EP-4137491-A1 | IMIDAZOLINONE DERIVATIVE AND USE THEREOF IN MEDICINE | Chengdu Baiyu Pharmaceutical Co., Ltd. (CN) | 2023-02-22 | — | — | EP | disclosed |
| EP-4137491-A1 | IMIDAZOLINONE DERIVATIVE AND USE THEREOF IN MEDICINE | Chengdu Baiyu Pharmaceutical Co., Ltd. (CN) | 2023-02-22 | — | — | EP | disclosed |
| US-4721799-A | POLYAMINE CURING AGENTS, FIBER REINFORCEMENT | AMOCO CORPORATION (US) | 1988-01-26 | — | — | US | disclosed |
| EP-0241931-A1 | Epoxy resins based on tetraglycidyl diamines | AMOCO CORPORATION (US) | 1987-10-21 | — | — | EP | disclosed |
| EP-0239804-A1 | Epoxy resins based on tetraglycidyl diamines and the use thereof for epoxy systems and prepregs | AMOCO CORPORATION (US) | 1987-10-07 | — | — | EP | disclosed |
| US-4680341-A | Epoxy resins based on tetraglycidyl diamines | UNION CARBIDE CORPORATION (US) | 1987-07-14 | — | — | US | disclosed |
| US-4421601-A | LACQUERS, INKS, PAINTS, TEXTILES, PAPER | BAYER AKTIENGESELLSCHAFT (DE) | 1983-12-20 | — | — | US | disclosed |
| US-4092243-A | CONTAINING TRIAZINE RINGS, SELECTIVE ABSORPTION OF HYDROCARBONS | BAYER AKTIENGESELLSCHAFT (DT) | 1978-05-30 | — | — | US | disclosed |
| US-4014863-A | LACQUERS, PRINTING INKS, PAINTS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-03-29 | — | — | US | disclosed |
| US-3957728-A | MODIFIED WITH S-TRIAZINES; ABSORBENTS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240277852-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | PIP4K2A, PIP4K2C, PIP4K2B | PARP1 1693/4885TDP1 1592/4885MAPT 1665/4885 |
| US-20230165867-A1 | IMIDAZOLIDINONE DERIVATIVES AND MEDICAL USE THEREOF | SYMPK, PAICS, CYP2C9 | PARP1 2313/4885TDP1 1092/4885MAPT 2312/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.