SCHEMBL436565

SCHEMBL436565

Cc1cc(C(=O)c2ccc(N)c(C)c2)ccc1N

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.56
NPC1 O15118 3/20 0.56
MITF O75030 1/20 0.56
POLB P06746 1/20 0.56
HTT P42858 3/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
MAPT P10636 5/20 0.52
TDP1 Q9NUW8 4/20 0.52
ALDH1A1 P00352 5/20 0.52
MAPK1 P28482 2/20 0.52
GAA P10253 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
CYP3A4 P08684 2/20 0.50
TSHR P16473 1/20 0.50
USP2 O75604 1/20 0.47
RAB9A P51151 1/20 0.47
HSD17B10 Q99714 1/20 0.47
THRB P10828 1/20 0.44
MAPK13 O15264 1/20 0.44
MAPK12 P53778 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13783385 0.92 MAPT (0.66) LMNANPC1MITFPOLBHTT
SCHEMBL7195606 0.92 LMNA (0.54) LMNANPC1MITFPOLBHTT
SCHEMBL4609604 0.90 POLB (0.57) LMNANPC1MITFPOLBHTT
SCHEMBL12490393 0.90 HTT (0.70) LMNANPC1MITFPOLBHTT
SCHEMBL6234574 0.89 MAPK1 (0.50) LMNANPC1MITFPOLBHTT
SCHEMBL7194336 0.87 NPC1 (0.78) LMNANPC1MITFPOLBHTT
SCHEMBL7190423 0.86 NPC1 (0.53) LMNANPC1MITFPOLBHTT
SCHEMBL1806409 0.84 PARP1 (0.50) LMNANPC1MITFPOLBHTT
SCHEMBL30241864 0.84 CDC25B (0.55) LMNANPC1POLBHTTSMN1; SMN2
SCHEMBL30508415 0.84 PRKCI (0.53) LMNANPC1MITFPOLBHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 278 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8080319-B2 Thermosetting resin composition and use thereof Kippon Kayaku Kabushiki Kaisha (JP) 2011-12-20 US claimed
US-20090286087-A1 Thermosetting Resin Composition and Use thereof NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2009-11-19 US claimed
US-20070009751-A1 Polyamic acid resin composition modified with laminate nanometer silica sheet and polyimide prepared therefrom CHANG CHUN PLASTICS CO., LTD. (TW) 2007-01-11 US claimed
US-7005163-B2 Organic-inorganic hybrid film material and its fabrication CHANG CHUN PLASTICS CO., LTD. (TW) 2006-02-28 US claimed
EP-1023168-B1 FIBER-REINFORCED PHTHALONITRILE COMPOSITE CURED WITH LOW-REACTIVITY AROMATIC AMINE CURING AGENT US GOV SEC NAVY (US) 2004-11-24 EP claimed
US-20040110014-A1 Organic-inorganic hybrid film material and its fabrication CHANG CHUN PLASTICS CO., LTD. (TW) 2004-06-10 US claimed
EP-1023168-A4 FIBER-REINFORCED PHTHALONITRILE COMPOSITE CURED WITH LOW-REACTIVITY AROMATIC AMINE CURING AGENT US NAVY (US) 2000-12-20 EP claimed
EP-1023168-A1 FIBER-REINFORCED PHTHALONITRILE COMPOSITE CURED WITH LOW-REACTIVITY AROMATIC AMINE CURING AGENT THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY OF THE NAVY (US) 2000-08-02 EP claimed
US-6001926-A Fiber-reinforced phthalonitrile composite cured with low-reactivity aromatic amine curing agent THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1999-12-14 US claimed
WO-1999017928-A1 FIBER-REINFORCED PHTHALONITRILE COMPOSITE CURED WITH LOW-REACTIVITY AROMATIC AMINE CURING AGENT THE GOVERNMENT OF THE UNITED STATES, REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1999-04-15 WO claimed
US-4886873-A ELASTICITY AND HEAT RESISTANCE DIRECTOR-GENERAL OF AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 1989-12-12 US claimed
EP-4691762-A1 ADHESIVE-ATTACHED METAL SUBSTRATE, AND LAMINATE ZACROS CORPORATION (KR) 2026-02-11 EP disclosed
US-20250261306-A1 ADHESIVE-EQUIPPED METAL SUBSTRATE AND LAMINATE ZACROS CORPORATION (JP) 2025-08-14 US disclosed
US-12365763-B2 Phthalonitrile resins, methods of making same and compositions thereof HUNTSMAN ADVANCED MATERIALS AMERICAS LLC 2025-07-22 US disclosed
WO-2025069645-A1 POLYMER ELECTROLYTE FUEL CELL SEALING MATERIAL 株式会社巴川コーポレーション 2025-04-03 WO disclosed
US-4026871-A Chain-extending phenolic end-capped polyimides UNIVERSITY OF NOTRE DAME (US) 1977-05-31 US disclosed
US-4026833-A CROSSLINKED FOAMS UNIVERSITY OF NOTRE DAME (US) 1977-05-31 US disclosed
US-3998786-A USEFUL FOR PREPARING COATINGS UNIVERSITY OF NOTRE DAME DU LAC (US) 1976-12-21 US disclosed
US-3996196-A Polyimide-metallo-phthalocyanines and their preparation UNIVERSITY OF NOTRE DAME DU LAC (US) 1976-12-07 US disclosed
US-3987003-A THERMALLY STABLE DIOXO AND DITHIO-BENZISOQUINOLINE COMPOSITIONS AND PROCESS OF SYNTHESIZING SAME THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 1976-10-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12365763-B2 Phthalonitrile resins, methods of making same and compositions thereof PNN, PAH, CUL4B LMNA 1315/4885NPC1 4297/4885MITF 75/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.