Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Triethylene Glycol SCHEMBL18221838 | 1.00 | MEN1 (0.65) | MEN1KMT2ATSHRMAPK1THRB | |
| Tetraethylene Glycol SCHEMBL2989827 | 0.97 | MEN1 (0.61) | MEN1KMT2ATSHRMAPK1THRB | |
| SCHEMBL30001767 | 0.88 | MEN1 (0.73) | MEN1KMT2ATSHRMAPK1THRB | |
| Triethylene Glycol SCHEMBL20972932 | 0.88 | MEN1 (0.73) | MEN1KMT2ATSHRMAPK1THRB | |
| Triethylene Glycol SCHEMBL30807519 | 0.88 | MEN1 (0.73) | MEN1KMT2ATSHRMAPK1THRB | |
| SCHEMBL30578802 | 0.88 | MEN1 (0.73) | MEN1KMT2ATSHRMAPK1THRB | |
| SCHEMBL30578803 | 0.88 | MEN1 (0.73) | MEN1KMT2ATSHRMAPK1THRB | |
| Hexaethylene Glycol SCHEMBL31031271 | 0.88 | MEN1 (0.73) | MEN1KMT2ATSHRMAPK1THRB | |
| Triethylene Glycol SCHEMBL18221837 | 0.88 | MEN1 (0.73) | MEN1KMT2ATSHRMAPK1THRB | |
| Tetraethylene Glycol SCHEMBL19990177 | 0.88 | MEN1 (0.73) | MEN1KMT2ATSHRMAPK1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113543771-A | Functionalized liposomes for imaging misfolded proteins | 阿尔兹卡生物科学公司 | 2021-10-22 | — | — | CN | disclosed |
| US-10125124-B2 | Formation of macromolecules using iterative growth and related compounds | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2018-11-13 | — | — | US | disclosed |
| US-20160272623-A1 | FORMATION OF MACROMOLECULES USING ITERATIVE GROWTH AND RELATED COMPOUNDS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10125124-B2 | Formation of macromolecules using iterative growth and related compounds | IGFBP6, IGFBP1, PGF | MEN1 1179/4885KMT2A 4101/4885TSHR 2782/4885 |
| US-20160272623-A1 | FORMATION OF MACROMOLECULES USING ITERATIVE GROWTH AND RELATED COMPOUNDS | IGFBP6, IGFBP1, PGF | MEN1 1179/4885KMT2A 4101/4885TSHR 2782/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.