SCHEMBL18068664

SCHEMBL18068664

O=S(=O)(O)C(F)(F)C(F)CCCC12CC3CC(CC(C3)C1)C2

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 8/20 0.39
GRIN2D O15399 3/20 0.39
GRIN3B O60391 3/20 0.39
GRIN1 Q05586 3/20 0.39
GRIN2A Q12879 3/20 0.39
GRIN2B Q13224 3/20 0.39
GRIN2C Q14957 3/20 0.39
GRIN3A Q8TCU5 3/20 0.39
EPHX1 P07099 1/20 0.33
ALDH1A1 P00352 2/20 0.32
GBA1 P04062 2/20 0.32
GBA2 Q9HCG7 2/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
GRM2 Q14416 1/20 0.31
GRM3 Q14832 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16000731 0.96 GRIN2D (0.40) EPHX2GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL23781721 0.76 GRIN2D (0.48) EPHX2GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL26942054 0.76 PRKCA (0.39) EPHX2ALDH1A1MEN1KMT2A
SCHEMBL18485657 0.75 GRIN2D (0.43) EPHX2GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL25684712 0.75 PRKCA (0.39) EPHX2ALDH1A1MEN1KMT2A
SCHEMBL12257078 0.73 LMNA (0.43) EPHX1ALDH1A1MEN1KMT2A
SCHEMBL21396819 0.73 EPHX2 (0.42) EPHX2GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL13965550 0.72 PRKCA (0.41) ALDH1A1MEN1KMT2A
SCHEMBL17577422 0.72 GRIN2D (0.46) EPHX2GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL19049859 0.72 CA12 (0.38) ALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160266488-A1 ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, PATTERN FORMING METHOD, METHOD FOR MANUFACTURING ELECTRONIC DEVICE, AND ELECTRONIC DEVICE FUJIFILM CORPORATION (JP) 2016-09-15 US disclosed