Zankiren

Zankiren

SCHEMBL180700

CC(C)C[C@H](O)[C@H](O)[C@H](CC1CCCCC1)NC(=O)[C@H](Cc1cscn1)NC(=O)[C@H](Cc1ccccc1)CS(=O)(=O)N1CCN(C)CC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ REN P00797 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Zankiren SCHEMBL8352631 1.00 REN (1.00) REN
Zankiren SCHEMBL8852548 1.00 REN (1.00) REN
Zankiren SCHEMBL29885493 1.00 REN (1.00) REN
Zankiren SCHEMBL7441825 1.00 REN (1.00) REN
Zankiren SCHEMBL121553 0.99 REN (0.99) REN
SCHEMBL14034941 0.88 REN (0.78) REN
SCHEMBL14008235 0.88 REN (0.78) REN
SCHEMBL8852557 0.83 REN (0.71) REN
SCHEMBL8904006 0.81 REN (0.69) REN
SCHEMBL30660206 0.80 REN (0.67) REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1351 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250206779-A1 ANGIOTENSIN-(1-9) ANALOGUE BASED ON D AMINO ACIDS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF UNIVERSIDAD DE CHILE (CL) 2025-06-26 — — US claimed
US-20250082608-A1 TREATMENT AND PREVENTION OF GLOMERULAR DISEASE SINGAPORE HEALTH SERVICES PTE LTD. (SG) 2025-03-13 — — US claimed
WO-2025050228-A1 PHARMACEUTICAL COMPOSITION COMPRISING A PEPTIDE OR A COMBINATION OF PEPTIDES AGONISTIC TO THE MAS, AT1 AND AT2 RECEPTORS PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE (CL) 2025-03-13 — — WO claimed
EP-4448096-A1 TREATMENT AND PREVENTION OF GLOMERULAR DISEASE Singapore Health Services Pte. Ltd. (SG) 2024-10-23 — — EP claimed
EP-4337675-A1 ANGIOTENSIN-(1-9) ANALOGUE BASED ON D AMINO ACIDS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF Universidad De Chile (CL) 2024-03-20 — — EP claimed
WO-2023111196-A1 TREATMENT AND PREVENTION OF GLOMERULAR DISEASE SINGAPORE HEALTH SERVICES PTE. LTD. (SG) 2023-06-22 — — WO claimed
WO-2022265697-A1 COMPOSITIONS FOR TREATING VIRAL INFECTIONS AND METHODS FOR SAME Tiger Development, LLC (US) 2022-12-22 — — WO claimed
US-20220370360-A1 COMPOSITIONS FOR TREATING VIRAL INFECTIONS AND METHODS FOR SAME ACCESS TO ADVANCED HEALTH INSTITUTE 2022-11-24 — — US claimed
WO-2022238734-A1 ANGIOTENSIN-(1-9) ANALOGUE BASED ON D AMINO ACIDS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF UNIVERSIDAD DE CHILE (CL) 2022-11-17 — — WO claimed
US-20210401751-A1 COMPOSITIONS FOR TREATING VIRAL INFECTIONS AND METHODS FOR SAME Tiger Development Inc. (US) 2021-12-30 — — US claimed
WO-2005070406-A1 COMBINATION OF ORGANIC COMPOUNDS NOVARTIS AG (CH) 2005-08-04 — — WO claimed
EP-1531879-A1 USE OF ORGANIC COMPOUNDS Novartis AG (CH) 2005-05-25 — — EP claimed
EP-1507558-A1 PHARMACEUTICAL COMPOSITION COMPRISING A RENIN INHIBITOR, A CALCIUM CHANNEL BLOCKER AND A DIURETIC Novartis AG (CH) 2005-02-23 — — EP claimed
US-20040266743-A1 Combination of an aldosterone receptor antagonist and a renin inhibitor PHARMACIA CORPORATION 2004-12-30 — — US claimed
WO-2004100871-A2 COMBINATION OF AN ALDOSTERONE RECEPTOR ANTAGONIST AND A RENIN INHIBITOR PHARMACIA CORPORATION (US) 2004-11-25 — — WO claimed
US-20040087484-A1 Treating sexual dysfunction associated with hypertension; angiotensin receptor blocker with either antihypertensive agent or HMG-CoA reductase inhibitor SAHOTA PRITAM SINGH (US) 2004-05-06 — — US claimed
WO-2004002549-A1 USE OF ORGANIC COMPOUNDS NOVARTIS AG (CH) 2004-01-08 — — WO claimed
WO-2003097098-A1 PHARMACEUTICAL COMPOSITION COMPRISING A RENIN INHIBITOR, A CALCIUM CHANNEL BLOCKER AND A DIURETIC NOVARTIS AG (CH) 2003-11-27 — — WO claimed
EP-1353727-A2 COMBINATIONS OF AN ANGIOTENSIN RECEPTOR ANTAGONIST AND AN ANTI-HYPERTENSIVE DRUGOR A STATIN, FOR THE TREATMENT OF SEXUAL DYSFUNCTION Novartis AG (CH) 2003-10-22 — — EP claimed
WO-2002043807-A2 COMBINATIONS OF AN ANGIOTENSIN RECEPTOR ANTAGONIST AND AN ANTI-HYPERTENSIVE DRUG OR A STATIN, FOR THE TREATMENT OF SEXUAL DYSFUNCTION NOVARTIS AG (CH) 2002-06-06 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040266743-A1 Combination of an aldosterone receptor antagonist and a renin inhibitor REN, AGTR1, AGTR2 REN 1/4885
US-20040087484-A1 Treating sexual dysfunction associated with hypertension; angiotensin receptor blocker with either antihypertensive agent or HMG-CoA reductase inhibitor AGTR1, HMGCR, AGTR2 REN 10/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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