Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 12/20 | 0.77 |
| ▸ | MAPT | P10636 | 7/20 | 0.77 |
| ▸ | THRB | P10828 | 4/20 | 0.77 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.77 |
| ▸ | RECQL | P46063 | 4/20 | 0.77 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.77 |
| ▸ | POLB | P06746 | 3/20 | 0.77 |
| ▸ | BLM | P54132 | 3/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.77 |
| ▸ | ATM | Q13315 | 3/20 | 0.77 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.77 |
| ▸ | MEN1 | O00255 | 2/20 | 0.77 |
| ▸ | APAF1 | O14727 | 2/20 | 0.77 |
| ▸ | GSR | P00390 | 2/20 | 0.77 |
| ▸ | PKM | P14618 | 2/20 | 0.77 |
| ▸ | MAOA | P21397 | 2/20 | 0.77 |
| ▸ | PPARG | P37231 | 2/20 | 0.77 |
| ▸ | HTT | P42858 | 2/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13116706 | 0.90 | APP (0.81) | APPMAPTTHRBMAPK1RECQL | |
| SCHEMBL18070377 | 0.89 | MAPT (0.60) | APPMAPTTHRBMAPK1RECQL | |
| SCHEMBL29400750 | 0.89 | MAPT (0.60) | APPMAPTTHRBMAPK1RECQL | |
| SCHEMBL18070266 | 0.88 | APP (0.70) | APPMAPTTHRBMAPK1RECQL | |
| Hydrochloric Acid SCHEMBL31114230 | 0.88 | MAPT (0.61) | APPMAPTTHRBMAPK1RECQL | |
| Methylene Blue Cation SCHEMBL29441543 | 0.87 | APP (1.00) | APPMAPTTHRBMAPK1RECQL | |
| Methylene Blue Cation SCHEMBL127316 | 0.87 | APP (1.00) | APPMAPTTHRBMAPK1RECQL | |
| Methylene Blue Cation SCHEMBL4227551 | 0.86 | APP (1.00) | APPMAPTTHRBMAPK1RECQL | |
| Methylene Blue Cation SCHEMBL29668541 | 0.85 | THRB (1.00) | APPMAPTTHRBMAPK1RECQL | |
| Methylene Blue Cation SCHEMBL30021960 | 0.85 | APP (0.97) | APPMAPTTHRBMAPK1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160263249-A1 | NEAR-INFRARED FLUORESCENT CONTRAST BIOIMAGING AGENTS AND METHODS OF USE THEREOF | BETH ISRAEL DEACONESS MEDICAL CENTER (US) | 2016-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160263249-A1 | NEAR-INFRARED FLUORESCENT CONTRAST BIOIMAGING AGENTS AND METHODS OF USE THEREOF | CD68, MSR1, CD47 | APP 3590/4885MAPT 3284/4885THRB 2423/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.