SCHEMBL1807246

SCHEMBL1807246

[O]CCc1ccc(Cl)cc1S(=O)(=O)O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
PSEN1 P49768 5/20 0.36
PSEN2 P49810 5/20 0.36
APH1B Q8WW43 5/20 0.36
NCSTN Q92542 5/20 0.36
APH1A Q96BI3 5/20 0.36
PSENEN Q9NZ42 5/20 0.36
ERCC1 P07992 1/20 0.35
ERCC4 Q92889 1/20 0.35
LMNA P02545 2/20 0.35
CYP3A4 P08684 2/20 0.35
ALOX15 P16050 2/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C19 P33261 1/20 0.35
MCL1 Q07820 2/20 0.34
NSD2 O96028 1/20 0.34
MMP14 P50281 1/20 0.34
CASP6 P55212 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1805112 0.90 ALDH1A1 (0.37) ALDH1A1L3MBTL1LMNACYP3A4ALOX15
SCHEMBL1809165 0.88 ALDH1A1 (0.36) ALDH1A1L3MBTL1LMNACYP3A4ALOX15
SCHEMBL1807248 0.86 ALDH1A1 (0.39) ALDH1A1L3MBTL1PSEN1PSEN2APH1B
SCHEMBL1806033 0.85 ALDH1A1 (0.37) ALDH1A1L3MBTL1PSEN1PSEN2APH1B
SCHEMBL1803078 0.84 TAAR1 (0.42) ALDH1A1L3MBTL1CYP3A4CYP1A2PTGES2
SCHEMBL1803077 0.84 ALDH1A1 (0.38) ALDH1A1L3MBTL1PSEN1PSEN2APH1B
SCHEMBL1805115 0.83 CA2 (0.42) ALDH1A1L3MBTL1PSEN1PSEN2APH1B
SCHEMBL1807032 0.82 PTGES2 (0.45) PTGES2
SCHEMBL1806035 0.81 PSEN1 (0.44) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL3793223 0.81 ALDH1A1 (0.36) ALDH1A1L3MBTL1LMNACYP3A4ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404036-B2 Water-soluble near-infrared absorbing coloring matters and aqueous inks containing same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2013-03-26 US disclosed
US-20110123784-A1 WATER-SOLUBLE NEAR-INFRARED ABSORBING COLORING MATTERS AND AQUEOUS INKS CONTAINING SAME NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2011-05-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110123784-A1 WATER-SOLUBLE NEAR-INFRARED ABSORBING COLORING MATTERS AND AQUEOUS INKS CONTAINING SAME IK, RB1, COL1A1 ALDH1A1 218/4885L3MBTL1 2085/4885PSEN1 1128/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.