SCHEMBL1807355

SCHEMBL1807355

COc1ccc(CO)cc1S(=O)(=O)O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDC25A P30304 1/20 0.53
CDC25B P30305 1/20 0.53
HIF1A Q16665 1/20 0.53
CA5A P35218 1/20 0.44
GSK3B P49841 1/20 0.44
CASR P41180 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.42
TTR P02766 1/20 0.42
NPC1 O15118 1/20 0.41
POLB P06746 1/20 0.41
RAB9A P51151 1/20 0.41
ALDH1A1 P00352 1/20 0.41
LMNA P02545 1/20 0.41
MAPT P10636 1/20 0.41
KMT2A Q03164 1/20 0.41
PTGES2 Q9H7Z7 1/20 0.41
ALPL P05186 2/20 0.41
PKM P14618 1/20 0.41
NR1I2 O75469 1/20 0.40
CA2 P00918 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1808055 0.87 CDC25A (0.51) CDC25ACDC25BHIF1ACA5AGSK3B
SCHEMBL1808393 0.86 CA5A (0.44) CDC25ACDC25BHIF1ACA5ASMN1; SMN2
SCHEMBL1807353 0.86 CDC25A (0.53) CDC25ACDC25BHIF1ACA5AGSK3B
SCHEMBL14097342 0.86 CDC25A (0.53) CDC25ACDC25BHIF1ACA5AGSK3B
SCHEMBL1807379 0.85 CDC25A (0.52) CDC25ACDC25BHIF1ACA5AGSK3B
SCHEMBL1807384 0.85 PKM (0.58) CA5AALDH1A1PTGES2PKMCA2
SCHEMBL1807376 0.85 CDC25A (0.52) CDC25ACDC25BHIF1ACA5AGSK3B
SCHEMBL1808052 0.83 CDC25A (0.51) CDC25ACDC25BHIF1ACA5AGSK3B
SCHEMBL23823918 0.82 TRIM24 (0.50) CDC25ACDC25BHIF1ACA5AGSK3B
SCHEMBL1802998 0.82 CDC25A (0.50) CDC25ACDC25BHIF1ACA5AGSK3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404036-B2 Water-soluble near-infrared absorbing coloring matters and aqueous inks containing same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2013-03-26 US disclosed
US-20110123784-A1 WATER-SOLUBLE NEAR-INFRARED ABSORBING COLORING MATTERS AND AQUEOUS INKS CONTAINING SAME NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2011-05-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110123784-A1 WATER-SOLUBLE NEAR-INFRARED ABSORBING COLORING MATTERS AND AQUEOUS INKS CONTAINING SAME IK, RB1, COL1A1 CDC25A 746/4885CDC25B 1760/4885HIF1A 1831/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.