SCHEMBL1807382

SCHEMBL1807382

COc1ccc(C[O])cc1S(N)(=O)=O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 2/20 0.55
CA2 P00918 6/20 0.47
CA9 Q16790 6/20 0.47
CA1 P00915 5/20 0.47
CA12 O43570 4/20 0.47
ADRA1D P25100 6/20 0.47
ADRA1A P35348 6/20 0.47
ADRA1B P35368 6/20 0.47
ADRB2 P07550 1/20 0.47
ADRB1 P08588 1/20 0.47
HTR1A P08908 1/20 0.47
ADRA2A P08913 1/20 0.47
DRD2 P14416 1/20 0.47
ADRA2B P18089 1/20 0.47
ADRA2C P18825 1/20 0.47
HTR2A P28223 1/20 0.47
HTR7 P34969 1/20 0.47
OPRM1 P35372 1/20 0.47
DRD3 P35462 1/20 0.47
HTR2B P41595 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1803675 0.87 PKM (0.56) PKMCA2CA9CA1CA12
SCHEMBL10640275 0.86 PKM (0.55) PKMCA2CA9CA1CA12
SCHEMBL1807393 0.86 PKM (0.50) PKMCA2CA9CA1CA12
SCHEMBL28732677 0.86 PKM (0.55) PKMCA2CA9CA1CA12
SCHEMBL24313922 0.85 PKM (0.54) PKMCA2CA9CA1CA12
SCHEMBL1807384 0.85 PKM (0.58) PKMCA2CA9CA1CA12
SCHEMBL10639502 0.83 PKM (0.53) PKMCA2CA9CA1CA12
SCHEMBL142264 0.83 KDM4E (0.62) PKMCA2CA9CA1CA12
SCHEMBL13985850 0.83 ADRA1D (0.54) PKMCA2CA9CA1CA12
SCHEMBL1807353 0.83 CDC25A (0.53) PKMCA2CA5AALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404036-B2 Water-soluble near-infrared absorbing coloring matters and aqueous inks containing same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2013-03-26 US disclosed
US-20110123784-A1 WATER-SOLUBLE NEAR-INFRARED ABSORBING COLORING MATTERS AND AQUEOUS INKS CONTAINING SAME NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2011-05-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110123784-A1 WATER-SOLUBLE NEAR-INFRARED ABSORBING COLORING MATTERS AND AQUEOUS INKS CONTAINING SAME IK, RB1, COL1A1 PKM 714/4885CA2 1279/4885CA9 1071/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.