Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.53 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 3/20 | 0.46 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.46 |
| ▸ | FLT3 | P36888 | 2/20 | 0.46 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.46 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13455388 | 0.84 | ALDH1A1 (0.61) | LMNAALDH1A1MAPTKDM4EDDAH1 | |
| SCHEMBL5498592 | 0.76 | ALDH1A1 (0.72) | LMNAALDH1A1MAPTKDM4EDDAH1 | |
| SCHEMBL79949 | 0.76 | LMNA (0.53) | LMNAALDH1A1MAPTKDM4EDDAH1 | |
| SCHEMBL4722581 | 0.76 | MAPT (0.53) | LMNAALDH1A1MAPTKDM4EDDAH1 | |
| SCHEMBL3868022 | 0.76 | MAPT (0.53) | LMNAALDH1A1MAPTKDM4EDDAH1 | |
| SCHEMBL26645428 | 0.76 | MAPT (0.53) | LMNAALDH1A1MAPTKDM4EDDAH1 | |
| SCHEMBL29881669 | 0.76 | ALDH1A1 (0.72) | LMNAALDH1A1MAPTKDM4EDDAH1 | |
| SCHEMBL6238353 | 0.73 | PIM1 (0.44) | LMNAMAPTPIM1CHEK1FLT3 | |
| SCHEMBL8807782 | 0.72 | KDM4E (0.48) | LMNAALDH1A1MAPTKDM4EDDAH1 | |
| SCHEMBL17272797 | 0.72 | ALDH1A1 (0.48) | LMNAALDH1A1MAPTKDM4EDDAH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4265601-A2 | USE OF BENZISOSELAZOLE DERIVATIVE FOR ANTI-CORONAVIRUS AND CONTROL OF INTERSTITIAL LUNG DISEASE (ILD) RELATED TO CORONAVIRUS | Shanghai Yuanxi Medicine Corp. (CN) | 2023-10-25 | — | — | EP | disclosed |
| US-20230210819-A1 | USE OF BENZISOSELAZOLE DERIVATIVE FOR ANTI-CORONAVIRUS AND CONTROL OF INTERSTITIAL LUNG DISEASE (ILD) RELATED TO CORONAVIRUS | SHANGHAI YUANXI MEDICINE CORP. (CN) | 2023-07-06 | — | — | US | disclosed |
| EP-3271354-A1 | NOVEL 3-INDOL SUBSTITUTED DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND METHODS FOR USE | Pfizer Inc (US) | 2018-01-24 | — | — | EP | disclosed |
| WO-2016147144-A1 | NOVEL 3-INDOL SUBSTITUTED DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND METHODS FOR USE | PFIZER INC. (US) | 2016-09-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230210819-A1 | USE OF BENZISOSELAZOLE DERIVATIVE FOR ANTI-CORONAVIRUS AND CONTROL OF INTERSTITIAL LUNG DISEASE (ILD) RELATED TO CORONAVIRUS | ACE, SARS1, ACE2 | LMNA 981/4885ALDH1A1 1235/4885MAPT 3470/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.