Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.43 |
| ▸ | FEN1 | P39748 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | IDH1 | O75874 | 1/20 | 0.40 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | APLNR | P35414 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.37 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18074955 | 0.81 | KDM4E (0.36) | RAB9AFEN1KDM4ENPC1L3MBTL1 | |
| SCHEMBL14096925 | 0.81 | ALOX5AP (0.49) | BTKRAB9AALOX5APFEN1KDM4E | |
| SCHEMBL15674574 | 0.78 | DHODH (0.47) | BTKRAB9AALOX5APFEN1KDM4E | |
| SCHEMBL20406251 | 0.78 | BTK (0.53) | BTKRAB9AALOX5APFEN1KDM4E | |
| SCHEMBL8344758 | 0.75 | MAPT (0.43) | BTKRAB9AALOX5APFEN1KDM4E | |
| SCHEMBL30592000 | 0.71 | IDH1 (0.41) | KDM4EALDH1A1IDH1MEN1POLB | |
| SCHEMBL29501242 | 0.71 | LOXL2 (0.47) | BTKRAB9AALOX5APFEN1NPC1 | |
| SCHEMBL15676581 | 0.71 | LOXL2 (0.47) | BTKRAB9AALOX5APFEN1NPC1 | |
| SCHEMBL21384169 | 0.71 | IDH1 (0.41) | KDM4EALDH1A1IDH1MEN1POLB | |
| SCHEMBL20361584 | 0.71 | HRH4 (0.45) | BTKRAB9AALOX5APFEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119019388-A | 5-And 6-azaindole compounds for inhibiting Bcr-Abl tyrosine kinase | 英莱汶公司 | 2024-11-26 | — | — | CN | disclosed |
| EP-3271350-B1 | SUBSTITUTED PYRIMIDINYLOXY PYRIDINE DERIVATIVES AS HERBICIDES | FMC CORP (US) | 2022-05-25 | — | — | EP | disclosed |
| US-11006631-B2 | Substituted pyrimidinyloxy pyridine derivatives as herbicides | FMC CORPORATION (US) | 2021-05-18 | — | — | US | disclosed |
| US-20180020664-A1 | SUBSTITUTED PYRIMIDINYLOXY PYRIDINE DERIVATIVES AS HERBICIDES | FMC CORPORATION | 2018-01-25 | — | — | US | disclosed |
| EP-3271350-A1 | SUBSTITUTED PYRIMIDINYLOXY PYRIDINE DERIVATIVES AS HERBICIDES | E. I. du Pont de Nemours and Company (US) | 2018-01-24 | — | — | EP | disclosed |
| WO-2016149315-A1 | SUBSTITUTED PYRIMIDINYLOXY PYRIDINE DERIVATIVES AS HERBICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2016-09-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11006631-B2 | Substituted pyrimidinyloxy pyridine derivatives as herbicides | DDT, CNPY2, NOX4 | BTK 980/4885RAB9A 2073/4885ALOX5AP 1441/4885 |
| US-20180020664-A1 | SUBSTITUTED PYRIMIDINYLOXY PYRIDINE DERIVATIVES AS HERBICIDES | DDT, CNPY2, NOX4 | BTK 980/4885RAB9A 2073/4885ALOX5AP 1441/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.