Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.32 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18075426 | 0.81 | BTK (0.43) | KDM4ERAB9AMEN1KMT2ANPC1 | |
| SCHEMBL31532200 | 0.78 | CYP1A2 (0.41) | RAB9AMEN1KMT2ANPC1GAA | |
| SCHEMBL16915375 | 0.78 | CYP1A2 (0.41) | RAB9AMEN1KMT2ANPC1GAA | |
| SCHEMBL16915418 | 0.68 | CYP1A2 (0.43) | RAB9AMEN1KMT2ANPC1GAA | |
| SCHEMBL4675603 | 0.67 | RAB9A (0.40) | RAB9ASMN1; SMN2TGFBR1L3MBTL1 | |
| SCHEMBL197509 | 0.65 | KDM4E (0.61) | KDM4ERAB9AMEN1KMT2ANPC1 | |
| SCHEMBL29577312 | 0.65 | KDM4E (0.61) | KDM4ERAB9AMEN1KMT2ANPC1 | |
| SCHEMBL197456 | 0.65 | CCR1 (0.46) | TGFBR1MAPK14L3MBTL1 | |
| SCHEMBL31504098 | 0.65 | CCR1 (0.46) | TGFBR1MAPK14L3MBTL1 | |
| SCHEMBL30912185 | 0.65 | SMN1; SMN2 (0.42) | RAB9AMEN1KMT2ANPC1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3271350-B1 | SUBSTITUTED PYRIMIDINYLOXY PYRIDINE DERIVATIVES AS HERBICIDES | FMC CORP (US) | 2022-05-25 | — | — | EP | disclosed |
| US-11006631-B2 | Substituted pyrimidinyloxy pyridine derivatives as herbicides | FMC CORPORATION (US) | 2021-05-18 | — | — | US | disclosed |
| US-20180020664-A1 | SUBSTITUTED PYRIMIDINYLOXY PYRIDINE DERIVATIVES AS HERBICIDES | FMC CORPORATION | 2018-01-25 | — | — | US | disclosed |
| EP-3271350-A1 | SUBSTITUTED PYRIMIDINYLOXY PYRIDINE DERIVATIVES AS HERBICIDES | E. I. du Pont de Nemours and Company (US) | 2018-01-24 | — | — | EP | disclosed |
| WO-2016149315-A1 | SUBSTITUTED PYRIMIDINYLOXY PYRIDINE DERIVATIVES AS HERBICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2016-09-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11006631-B2 | Substituted pyrimidinyloxy pyridine derivatives as herbicides | DDT, CNPY2, NOX4 | KDM4E 1907/4885RAB9A 2073/4885MEN1 4013/4885 |
| US-20180020664-A1 | SUBSTITUTED PYRIMIDINYLOXY PYRIDINE DERIVATIVES AS HERBICIDES | DDT, CNPY2, NOX4 | KDM4E 1907/4885RAB9A 2073/4885MEN1 4013/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.