Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | AGER | Q15109 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18078991 | 0.91 | KDM4E (0.36) | TMEM97SIGMAR1KMT2AKDM4EALDH1A1 | |
| SCHEMBL18078985 | 0.88 | CYP1A2 (0.45) | KMT2AKDM4EALDH1A1ALOX15RAD52 | |
| SCHEMBL18078984 | 0.85 | KMT2A (0.35) | TMEM97SIGMAR1KMT2AKDM4EALDH1A1 | |
| SCHEMBL18078983 | 0.83 | SIGMAR1 (0.45) | TMEM97SIGMAR1KDM4EALDH1A1HPGD | |
| SCHEMBL18078994 | 0.78 | ALOX15 (0.43) | KMT2AKDM4EALDH1A1ALOX15RAD52 | |
| SCHEMBL18078989 | 0.78 | TMEM97 (0.37) | TMEM97SIGMAR1RAD52 | |
| SCHEMBL18078990 | 0.78 | TMEM97 (0.37) | TMEM97SIGMAR1RAD52 | |
| SCHEMBL22271947 | 0.76 | KDM4E (0.44) | TMEM97SIGMAR1KMT2AKDM4EALDH1A1 | |
| SCHEMBL16647663 | 0.74 | HTT (0.48) | KMT2AKDM4EALDH1A1ALOX15RAD52 | |
| SCHEMBL18078986 | 0.73 | MAPK1 (0.43) | KMT2AKDM4EALDH1A1HPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10040850-B2 | Protecting group comprising a purification tag | ASCENDIS PHARMA A/S (DK) | 2018-08-07 | — | — | US | disclosed |
| US-20160257739-A1 | PROTECTING GROUP COMPRISING A PURIFICATION TAG | ASCENDIS PHARMA A/S (DK) | 2016-09-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160257739-A1 | PROTECTING GROUP COMPRISING A PURIFICATION TAG | GSTA2, GSTP1, MLN | TMEM97 3081/4885SIGMAR1 3891/4885KMT2A 1371/4885 |
| US-10040850-B2 | Protecting group comprising a purification tag | GSTA2, GSTP1, MLN | TMEM97 3081/4885SIGMAR1 3891/4885KMT2A 1371/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.